Evidence map›Paper›PMID 41074155›Full record

ArticleEnvironmental health : a global access science source2025

Exposure to consecutive extreme ozone-heatwave events and neurological disorders: a retrospective cohort study in Nanjing, China.

Haili Ren, Yizhang Xia, Tianchi Zhuang, Yang Li, Yu Chen, Wei Huang, Peijie Jiang, Xia Tang, Shuwen Han, Yan Cui and 2 more

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Haili RenSchool of Nursing, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, P. R. China.
Yizhang XiaZigong Center for Disease Control and Prevention, 826 Huichuan Road, Ziliujing District, Zigong, 643000, P. R. China.
Tianchi ZhuangSchool of Nursing, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, P. R. China.
Yang LiSichuan Provincial Center for Disease Control and Prevention, 6 Zhongxue Road, Wuhou District, Chengdu, 610041, P. R. China.
Yu ChenSchool of Health and Intelligent Engineering, Chengdu Medical College, No. 783, Xindu Road, Xindu District, Chengdu, China.
Wei HuangZigong Center for Disease Control and Prevention, 826 Huichuan Road, Ziliujing District, Zigong, 643000, P. R. China.
Peijie JiangXinqiao Hospital, Army Medical University, 83 Xinqiao Road, Shapingba District, Chongqing, 400037, P. R. China.
Xia TangSchool of Nursing, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, P. R. China.
Shuwen HanSchool of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, P. R. China.
Yan CuiSchool of Nursing, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, P. R. China. cyan_njmu@163.com.
Jiemiao ShenSchool of Nursing, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, P. R. China. jiemiao_shen@163.com.
Minghui JiSchool of Nursing, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, P. R. China. jiminghui@njmu.edu.cn.

Funding

Jiangsu Provincial Health Commission Public Health Research Project Ym2023064Nanjing Preventive Medicine Research Project NJYFKT202409the Project of "Nursing Science" Funded by the 4th Priority Discipline Development Program of Jiangsu Higher Education Institutions Jiangsu Education Department (2023) No.11
6 · The paper itself

Abstract

objectivesIn the context of global warming and escalating urbanization, occurrences of extreme ozone (EO) and heatwave (HW) events are increasingly frequent. However, studies on the impact of consecutive extreme ozone and heatwave (EO-HW) events on hospitalizations for neurological disorders (ND) and related economic burdens remains limited. Our study aimed to explore the impacts of these events on ND hospitalizations, length of stay, and related costs, with a specific focus on quantifying the impacts of consecutive extreme events of varying durations.

methodsTime-series analysis was performed to investigate the relationships between consecutive O

resultsExposure to EO-HW events were associated with an increased risk of hospitalization for ND, with this risk persisting from lag 1 day (1.097, 95% CI: 1.005,1.198) to lag 4 days (1.071, 95% CI: 1.004,1.139). Significant associations were particularly evident in male (highest RR value 1.092, 95% CI: 1.016,1.173) and aged < 65 years (highest RR value 1.124, 95% CI: 1.008,1.254). Furthermore, exposure to EO-HW events were found to result in longer length of stay and higher hospitalization costs compared to exposure to HW events alone.

conclusionsConsecutive EO-HW events significantly increase the risk of hospitalization and the economic burden of ND. Local authorities should consider incorporating early warning information and public health interventions for consecutive extreme weather into existing early warning systems. Neglecting to do so will likely result in higher associated illness rates and economic burdens.

Indexed as

Air PollutantsEnvironmental ExposureExtreme HeatHospitalizationNervous System DiseasesOzoneAdolescentAdultAgedAged, 80 and overChildChild, PreschoolChinaFemaleHumansInfantAir PollutantsOzoneCompound eventsHeatwavesHospitalizationNeurological disordersOzone

Identifiers

PMID41074155
PMCPMC12512602

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.