Evidence map›Paper›PMID 41074140›Full record

ArticleBMC health services research2025

Advancing quadruple helix theory for health systems innovation: evidence from Ageing@Coimbra.

Alessandra Ricciardelli, Lorenzo Mercurio, Claudia Salvatore

Abstract read
In one paragraph

Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alessandra RicciardelliDepartment of Economics, Statistics and Entrepreneurship, Universitas Mercatorum, Piazza Mattei, 10, Roma, RM, 00186, Italy. alessandra.ricciardelli@unimercatorum.it.
Lorenzo MercurioDepartment of Public Health, University of Naples Federico II, Via S. Pansini, 5, Naples, 80131, Italy.
Claudia SalvatoreDepartment of Public Health, University of Naples Federico II, Via S. Pansini, 5, Naples, 80131, Italy.

Funding

Ministry of Univeristy and Research of Italy E63C22002050006
6 · The paper itself

Abstract

backgroundSocietal challenges in public health call for innovation to enhance health outcomes and equity. This study explores the application of the Quadruple Helix (QH) model—engaging academia, government, industry, and civil society—in driving healthcare innovation at the regional level.

methodsA qualitative case study approach was adopted, focusing on the Ageing@Coimbra Reference Site. Data sources included policy reports, secondary literature, and twelve semi-structured interviews with key stakeholders. A thematic analysis was conducted to examine tangible and intangible outputs and the role of local ecosystem dynamics.

resultsThe findings reveal that Ageing@Coimbra leveraged QH collaboration to generate both tangible outcomes (e.g., integrated care models, digital health tools) and intangible benefits (e.g., civic engagement, patient empowerment). The local ecosystem played a critical role in aligning multi-sectoral actors and enabling participatory governance.

conclusionsThe QH model emerges as a viable framework for advancing regional healthcare innovation. Ageing@Coimbra illustrates how local embeddedness and cross-sectoral trust can foster scalable, community-driven solutions. The study provides actionable insights for policymakers aiming to replicate similar strategies elsewhere.

Indexed as

Delivery of Health CareOrganizational InnovationHumansInterviews as TopicQualitative ResearchActive and healthy ageingCollaborative innovationHealth ecosystemsInnovationQuadruple helixSustainability

Identifiers

PMID41074140
PMCPMC12512296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.