Evidence map›Paper›PMID 41074132›Full record

ArticleVirology journal2025

Isolation and genetic characterization of parvovirus from Bengal tiger in China.

Ye Wang, Shuyi Han, Yi Li, Guohui Yuan, Yanan Xing, Wanqian Chen, Mengyan Cheng, Hongxuan He

Abstract read
In one paragraph

Article in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ye Wang *Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Shuyi Han *Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Yi LiInstitute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Guohui YuanInstitute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Yanan XingInstitute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Wanqian ChenInstitute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Mengyan ChengInstitute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Hongxuan HeInstitute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China. hehx@ioz.ac.cn.

Funding

National Key R & D Program of China 2022YFC2601602
6 · The paper itself

Abstract

backgroundCanine parvovirus (CPV) poses an emerging threat to endangered felids, yet its epidemiology and evolutionary dynamics in tigers remain poorly characterized.

methodsPathogen detection was performed through necropsy, colloidal gold assays, and PCR on a deceased Bengal tiger, followed by genetic and molecular characterization of the identified CPV.

resultsThis study isolated a CPV-2c strain (HNSY-031) from captive Bengal tigers. Genetic analysis revealed its closest relationship to Vietnamese canine parvoviruses, with 100% identity to CPV strains circulating in China and Vietnam since 2020. Molecular characterization identified 12 amino acid mutations within the VP2 protein, including key residues associated with host adaptation and viral evolution.

conclusionsThe isolated CPV-2c strain may have originated from multiple potential sources, including contact with domestic or wild animals or contaminated environments. These findings highlight the necessity of implementing comprehensive biosecurity protocols around wildlife facilities, expanding vaccination programs for animals in surrounding regions, and establishing ongoing surveillance systems to monitor potential sources of pathogen exposure.

Indexed as

Parvoviridae InfectionsParvovirus, CanineTigersAnimalsCapsid ProteinsChinaPhylogenyCapsid ProteinsBengal tigerCPVIsolationMutationPCRPhylogenyVP2

Identifiers

PMID41074132
PMCPMC12512266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.