Evidence map›Paper›PMID 41074127›Full record

ArticleBMC complementary medicine and therapies2025

Cerebellar transcranial direct current stimulation combined with virtual reality training for the balance of older adults: study protocol for a randomized controlled trial.

Mengjie Zhang, Ting He, Yidi Xu, Chenrui Ma, Xindi Guo, Yuning Shen, Wenxin Niu

Abstract readClinical Trial Protocol
In one paragraph

Article in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengjie Zhang *Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, No. 2209 Guangxing Road, Songjiang District, Shanghai, China.
Ting He *Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, No. 2209 Guangxing Road, Songjiang District, Shanghai, China.
Yidi XuShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, No. 2209 Guangxing Road, Songjiang District, Shanghai, China.
Chenrui MaShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, No. 2209 Guangxing Road, Songjiang District, Shanghai, China.
Xindi GuoShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, No. 2209 Guangxing Road, Songjiang District, Shanghai, China.
Yuning ShenShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, No. 2209 Guangxing Road, Songjiang District, Shanghai, China.
Wenxin NiuShanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, No. 2209 Guangxing Road, Songjiang District, Shanghai, China. niu@tongji.edu.cn.ORCID http://orcid.org/0000-0003-1349-4524

Funding

National clinical key specialty construction project of China Z155080000004Shanghai Research Center of Rehabilitation Medicine (Top Priority Research Center of Shanghai) 2023ZZ02027Shanghai Yangzhi Rehabilitation Hospital Clinical Research Cultivation Program YNPP-2024CRTS010Shanghai Yangzhi Rehabilitation Hospital Youth Talent Project 2022QNRC14/2023QNRC15Songjiang Scientific and Technological Project 2023SJKJGG81
6 · The paper itself

Abstract

backgroundFalls are a major public safety issue, and improving the posture control ability of elderly people is highly important for preventing falls. Transcranial direct current stimulation (tDCS) and virtual reality-based balance training (VRBT) have been proven to be effective in improving postural stability and balance ability. The combination of these two methods may achieve better therapeutic effects. At present, there is a lack of research on the effects of tDCS combined with VRBT on postural stability and fall prevention in elderly individuals.

methodsThis 4-week single-blind, parallel-group randomized controlled trial will allocate 64 participants into the experimental or control group at a 1:1 ratio. The experimental group will undergo cerebellar tDCS combined with VRBT, whereas the control group will receive sham cerebellar tDCS paired with conventional exercise guidance. The outcome measures will be single leg stance with eyes closed, timed up and go, activities-specific balance confidence scale, modified falls efficacy scale, center of pressure measurements, and functional near-infrared spectroscopy. Assessments will be conducted at 0, 4, 8 and 12 weeks. DISCUSSION: Studies examining the effects of cerebellar tDCS combined with VRBT on postural stability and fall risk among older adults are lacking. This study aims to comprehensively assess the effects of cerebellar tDCS combined with VRBT on postural stability and balance function through clinical scales and objective instrumental assessments. The findings of this study are anticipated to enhance existing intervention strategies for fall prevention and inspire researchers to develop innovative treatment methods for older adults.

trial registrationChinese Clinical Trial Registry, ChiCTR2300078998, Registered on 22 December 2023.

Indexed as

Accidental FallsCerebellumExercise TherapyPostural BalanceTranscranial Direct Current StimulationVirtual RealityAgedFemaleHumansMaleRandomized Controlled Trials as TopicSingle-Blind MethodBalanceFall preventionFunctional near-infrared spectroscopyPostural stabilityTranscranial direct current stimulationVirtual reality

Identifiers

PMID41074127
PMCPMC12512832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.