Evidence map›Paper›PMID 41074046›Full record

ArticleBMC women's health2025

Interval between diagnosis and treatment of cervical cancer in Brazil: comparative analysis of cases with and without diagnosis prior to arrival at the hospital unit.

Letícia Gabriella Souza da Silva, Paulo Vitor de Souza Silva, Maria Fernanda Dantas Chaves, Ana Camilly da Costa Cruz, Jonas Eduardo Monteiro Dos Santos, Nayara Priscila Dantas de Oliveira, Marianna de Camargo Cancela, J Smith Torres-Roman, Dyego Leandro Bezerra de Souza

Abstract readComparative Study
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Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Letícia Gabriella Souza da SilvaDepartment of Collective Health; Graduate Program in Collective Health, Federal University of Rio Grande do Norte - UFRN. Natal-RN, Natal-RN, Brazil.
Paulo Vitor de Souza SilvaDepartment of Collective Health; Graduate Program in Collective Health, Federal University of Rio Grande do Norte - UFRN. Natal-RN, Natal-RN, Brazil.
Maria Fernanda Dantas ChavesDepartment of Collective Health; Graduate Program in Collective Health, Federal University of Rio Grande do Norte - UFRN. Natal-RN, Natal-RN, Brazil.
Ana Camilly da Costa CruzDepartment of Collective Health; Graduate Program in Collective Health, Federal University of Rio Grande do Norte - UFRN. Natal-RN, Natal-RN, Brazil.
Jonas Eduardo Monteiro Dos SantosEscola Nacional de Saúde Pública - Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Nayara Priscila Dantas de OliveiraPostgraduate Program in Rehabilitation and Functional Performance (PPGRDF), University of Pernambuco (UPE), Petrolina, Pernambuco, Brazil.
Marianna de Camargo CancelaResearch and Innovation Coordination, National Cancer Institute (INCA), Ministry of Health, Rio de Janeiro-RJ, Brazil.
J Smith Torres-RomanUniversidad Científica del Sur, Lima, Peru.
Dyego Leandro Bezerra de SouzaDepartment of Collective Health; Graduate Program in Collective Health, Federal University of Rio Grande do Norte - UFRN. Natal-RN, Natal-RN, Brazil. dyego.souza@ufrn.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTimely initiation of cancer treatment is essential to improving outcomes and reducing mortality. In Brazil, Federal Law No. 12.732/12 mandates that patients with confirmed cancer diagnoses begin treatment within 60 days. This study aimed to assess compliance with this law among women diagnosed with cervical cancer, comparing cases with and without a prior diagnosis at the time of hospital admission.

methodsEcological study of temporary series, based on data from the Integrator of Hospital Cancer Records (IRHC). The cases were divided into two groups (cases diagnosed during hospital care and those with a previous diagnosis) and analyzed in the periods before (2006 to 2012) and after the enactment of the law (2013 to 2019). The percentage trend of adherence was analyzed by the Joinpoint Regression Program.

resultsAmong 120,311 eligible cases, 31.7% (n = 38,143) were diagnosed at the hospital, and 68.3% (n = 82,168) had a prior diagnosis. Overall, 43.2% of women initiated treatment within 60 days. After the law was enacted, the proportion of timely treatment decreased to 66.7% in the no prior diagnosis group and 28.7% in the prior diagnosis group. Significant regional and interstate disparities were observed. Joinpoint analysis revealed both increasing and decreasing trends across states, with notable declines in timely treatment among women with a prior diagnosis.

conclusionCompliance with the 60-day treatment law remains suboptimal, particularly among women with a prior cervical cancer diagnosis. These disparities suggest persistent barriers in patient navigation and systemic inefficiencies within Brazil's public healthcare network. Our findings underscore the need for strengthening integrated care pathways and implementing national patient navigation programs to ensure timely cancer treatment.

Indexed as

Time-to-TreatmentUterine Cervical NeoplasmsAdultAgedBrazilFemaleHospitalizationHumansMiddle AgedTime FactorsCervical neoplasmsHospital recordsLaw enforcementTime to treatmentUnified health system

Identifiers

PMID41074046
PMCPMC12512830

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.