Observational studyBMC infectious diseases2025
Characteristics and mortality of children living with HIV/TB coinfection in a tertiary hospital in a resource-limited setting.
Observational study in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundIn Indonesia, children living with human immunodeficiency virus (HIV) face a heightened risk of tuberculosis (TB) coinfection. This study aims to explore the clinical characteristics and mortality of children with HIV/TB coinfection.
methodsA retrospective observational study was conducted on children diagnosed with HIV/TB coinfection and treated between 2017 and 2021 in Dr. M. Djamil Central Hospital, Padang City, Indonesia.
resultsTwenty-seven children were diagnosed with HIV/TB coinfection. Most children were male, aged five years or older, and resided in rural areas. All patients exhibited HIV clinical stage III or IV, with a median (IQR) CD4 count of 49 (18-534) cells/mm
conclusionsThis study highlights the considerable mortality risk among children living with HIV/TB coinfection, particularly emphasizing the significance of addressing severe anemia and pneumonia as contributing factors.
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