ArticleBMC oral health2025
Facial volume reduction and masticatory function after masseter botulinum toxin injection: a prospective study.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Perception of patients with temporomandibular disorders of the effects of botulinum toxin application: a retrospective cross-sectional observational study.Clinical oral investigations · 2026Observational
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBotulinum toxin type A (BTX-A) is widely used for masseter reduction to improve lower facial contour. While its esthetic effects are well established, the potential impact on masticatory function remains unclear, particularly in healthy individuals. This study aimed to evaluate changes in facial volume, patient satisfaction, and perceived chewing function following BTX-A injection.
methodsA quasi-experimental clinical trial was conducted in 24 healthy adults who received bilateral masseter injections of BTX-A (50 units total). Lower face volume was assessed using 3D stereophotogrammetry at baseline and at 4, 8, and 12 weeks post-injection. Patient satisfaction was measured using the FACE-Q™ questionnaire, and masticatory function was assessed with the Chewing Function Questionnaire (CFQ) and visual analog scale (VAS). Friedman and Wilcoxon signed-rank tests were used for statistical analysis.
resultsSignificant reductions in lower face volume were observed at all follow-up time points (p < 0.05), with the greatest change occurring by week 12. Satisfaction scores with facial appearance and treatment outcome significantly increased. Masticatory function remained stable, with no significant changes in CFQ or VAS scores. Participants reported no perceived decline in chewing ability throughout the study period.
conclusionOur results suggest that botulinum toxin injection into the masseter muscle may reduce lower face volume and improve patient satisfaction without compromising perceived masticatory function in healthy adults. These findings provide preliminary evidence for the esthetic application of BTX-A and may contribute to future investigations into its potential roles in areas such as bruxism management and prosthodontic planning.
trial registrationTCTR20240617001. Registered on June 17th, 2024.
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