Evidence map›Paper›PMID 41073942›Full record

ArticleBMC cancer2025

Thermostable enzyme isoforms, continuously producing monocomponent superoxide radicals, from human postoperative serous fluids: isolation and properties.

R M Simonyan, M A Babayan, H H Yekmalyan, S G Simonyan, K T Papazyan, S A Stepanyan, H K Sarkavagyan, G M Simonyan, L V Darbinyan, K V Simonyan and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

R M SimonyanLaboratory of Metabolism of Reactive Oxygen, H. Buniatyan Institute of Biochemistry NAS RA, Yerevan, 0014, Armenia.
M A BabayanLaboratory of Metabolism of Reactive Oxygen, H. Buniatyan Institute of Biochemistry NAS RA, Yerevan, 0014, Armenia.
H H YekmalyanLaboratory of Metabolism of Reactive Oxygen, H. Buniatyan Institute of Biochemistry NAS RA, Yerevan, 0014, Armenia.
S G SimonyanYerevan State Medical University Named After M. Heratsi, Yerevan, 0025, Armenia.
K T PapazyanYerevan State Medical University Named After M. Heratsi, Yerevan, 0025, Armenia.
S A StepanyanYerevan State Medical University Named After M. Heratsi, Yerevan, 0025, Armenia.
H K SarkavagyanYerevan State Medical University Named After M. Heratsi, Yerevan, 0025, Armenia.
G M SimonyanLaboratory of Metabolism of Reactive Oxygen, H. Buniatyan Institute of Biochemistry NAS RA, Yerevan, 0014, Armenia.
L V DarbinyanLaboratory Sensorimotor Integration, Orbeli Institute of Physiology NAS RA, Yerevan, 0028, Armenia. lilitdarbinyan@physiol.sci.am.
K V SimonyanLaboratory of Neuroendocrine Relationships, Orbeli Institute of Physiology NAS RA, Yerevan, 0028, Armenia.
S G ChailyanDepartment of Biochemistry of Neurohormones, H. Buniatyan Institute of Biochemistry NAS RA, Yerevan, 0014, Armenia.
M A SimonyanLaboratory of Metabolism of Reactive Oxygen, H. Buniatyan Institute of Biochemistry NAS RA, Yerevan, 0014, Armenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Free radicals are generated in the body through endogenous and exogenous systems, with their overproduction linked to chronic diseases such as cancer. Interestingly, chemotherapeutic drugs utilize free radicals to induce apoptosis in cancer cells, highlighting their dual nature. This study explores the therapeutic potential of free-radical-generating compounds in solid tumor treatment. Using a patented universal method, superoxide (O

Indexed as

SuperoxidesBreast NeoplasmsEnzyme StabilityFemaleFlavin-Adenine DinucleotideHumansIsoenzymesPostoperative PeriodStomach NeoplasmsFlavin-Adenine DinucleotideIsoenzymesSuperoxidesBreast cancerLiver cirrhosisMonocomponent superoxide radicals (O2 −)Serous fluidStomach cancerSuperoxide (O2 −) producing enzymes

Identifiers

PMID41073942
PMCPMC12512730

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.