Evidence map›Paper›PMID 41073937›Full record

ArticleBMC oral health2025

Populational influence on cephalometric landmark identification: performance of two AI-driven software programs in Brazilian and Korean images.

Thaisa Pinheiro Silva, Giovanna Sachs Puntigam, Maria Fernanda Silva Andrade-Bortoletto, Wilton Mitsunari Takeshita, Christiano Oliveira-Santos, Deborah Queiroz Freitas

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Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Thaisa Pinheiro SilvaDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, 13414-903, Brazil. thaisapinheirosilva@hotmail.com.
Giovanna Sachs PuntigamDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, 13414-903, Brazil.
Maria Fernanda Silva Andrade-BortolettoDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, 13414-903, Brazil.
Wilton Mitsunari TakeshitaDepartment of Oral Diagnosis, Division of Oral Radiology, , School of Dentistry of Araçatuba, Paulista State University (UNESP), Araçatuba, Sao Paulo, 16015-050, Brazil.
Christiano Oliveira-SantosDepartment of Diagnosis and Oral Health, University of Louisville School of Dentistry, Louisville, KY, U.S.A.
Deborah Queiroz FreitasDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, 13414-903, Brazil.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 0001
6 · The paper itself

Abstract

objectiveTo assess the performance of cephalometric landmark identification performed by two AI-driven software programs in images from different populations (Brazilian and Korean).

methodsSixty lateral cephalometric radiographs (30 Brazilian and 30 Korean) were analyzed. The Brazilian images were acquired using the Orthophos XG 5/Ceph device, while the Korean images were obtained from the International Symposium on Biomedical Imaging 2015 database. Images of patients with permanent dentition were included, excluding those with poor head positioning or severe craniofacial deformities. Twenty cephalometric landmarks were identified by two examiners used as the reference standard. Two AI-driven software programs, CefBot™ (Brazil) and WebCeph™ (Korea), automatically identified the same landmarks. Coordinate values for each landmark were measured using ImageJ, and the data were analyzed with Analysis of Variance and Dunnett's post-hoc test.

resultsThe Brazilian software showed high accuracy in identifying landmarks on Brazilian images (90%) but was less precise on Korean images (80%), with significant discrepancies in the Glabella, Menton L, Basion, and Orbitale landmarks. Similarly, the Korean software had a higher accuracy in its own population (95%) than in another population (85%), with notable inaccuracies in the Menton L, Basion, and Porion landmarks.

conclusionDiscrepancies in the identification of specific landmarks, such as Glabella and Menton L, suggest that the accuracy of the software may be influenced by the training process itself and by the population origin of the training data.

Indexed as

Anatomic LandmarksCephalometryImage Processing, Computer-AssistedSoftwareBrazilHumansRepublic of KoreaArtificial intelligenceCephalometryImage processing, Computer-AssistedRadiography, dental

Identifiers

PMID41073937
PMCPMC12512714

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