Evidence map›Paper›PMID 41073897›Full record

ArticleBMC plant biology2025

Overexpression of OsDUF846.2 enhances the sensitivity of rice to salt and heat stresses.

Jiali Zhu, Ziyi Wang, Hao Chen, Mingfei Chen, Xiulin Zhao, Caiyao Mao, Yijuan Kong, Juan Yang, Xiaomei Jia, Xiaoying Ye and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiali Zhu *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Ziyi Wang *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Hao ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Mingfei ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Xiulin ZhaoState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Caiyao MaoState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Yijuan KongState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Juan YangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Xiaomei JiaState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Xiaoying YeState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Rongjun ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Jianqing ZhuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Jun ZhuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China.
Lihua LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, China. lilihua1976@sicau.edu.cn.

Funding

the Sichuan Province Science and Technology Program 2022ZDZX0012
6 · The paper itself

Abstract

Soil salinity and heat stress are major abiotic stress factors restricting rice growth, development, and yield potential. DUFs (Domains of Unknown Function) are proteins with structurally conserved but functionally undefined domains, widely present across organisms. The DUF846 family has been demonstrated to participate in plant growth and development as well as trans-Golgi network sorting and secretion. However, their functional roles in abiotic stress tolerance responses in rice remain poorly understood. In this study, we focused on OsDUF846.2, a member of the rice DUF846 family. Our investigation revealed that OsDUF846.2 responds to both salt and heat stress in rice. Following salt and heat stress treatments, OsDUF846.2 overexpression lines exhibited more severe damage, lower survival rates, elevated reactive oxygen species (ROS) and malondialdehyde (MDA) accumulation, reduced antioxidant enzyme activities, and decreased proline and soluble sugar contents compared to wild type (WT). Transcriptome analysis indicated that OsDUF846.2 may enhance the sensitivity of rice to salt stress and heat stress by regulating salt stress-related pathways such as cytoskeletal stability and antioxidant defense system, and heat stress-related pathways such as protein homeostasis maintenance and RNA metabolism. These findings indicate that OsDUF846.2 negatively regulates the response of rice to salt stress and heat stress.

Indexed as

Heat-Shock ResponseOryzaPlant ProteinsSalt StressGene Expression Regulation, PlantHot TemperatureMalondialdehydePlants, Genetically ModifiedReactive Oxygen SpeciesMalondialdehydePlant ProteinsReactive Oxygen SpeciesDUFHeat stressReactive oxygen speciesRiceSalt stress

Identifiers

PMID41073897
PMCPMC12512708

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.