ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Current status and influencing factors of cancer-related fatigue in gastric cancer patients undergoing chemotherapy: A cross-sectional study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
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- Prevalence and its associated factors of cancer-related fatigue among liver cancer patients: a cross-sectional study.Scientific reports · 2026Article
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5 authors.
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Abstract
purposeTo investigate the current status of CRF and identify its influencing factors in patients undergoing chemotherapy for gastric cancer.
methodsA total of 525 patients receiving chemotherapy for gastric cancer were recruited from a tertiary general hospital in China. Data were collected using a set of standardized questionnaires. Stepwise multiple linear regression was applied to determine the impact of variables that were statistically significant (P < 0.05) in independent sample t tests, one-way ANOVA, and correlation analyses on fatigue levels. All statistical tests were two-sided, with a significance level set at α = 0.05.
resultsThe median (interquartile range) scores for total CRF, physical fatigue, emotional fatigue, and cognitive fatigue were 21.00 (15.00-27.00), 8.00 (4.00-12.00), 9.00 (7.00-11.00), and 4.00 (1.00-6.00), respectively. Overall, 57.2% of patients experienced moderate to severe fatigue. Multivariate analysis showed that female gender, nutritional risk status, poor sleep status, depression, and pain were significantly associated with higher CRF in patients undergoing chemotherapy for gastric cancer, together explaining 31.6% of the total variance.
conclusionCRF is highly prevalent among patients with gastric cancer and is influenced by multiple factors. These findings provide scientific evidence for the early identification of high-risk groups and the development of personalized intervention programs.
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