Evidence map›Paper›PMID 41073768›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2025

Association of NICU design on neurodevelopmental outcomes in preterm neonates born at less than 29 weeks' gestation: a retrospective observational study.

Mohammed Ellebany, Kamini Raghuram, Mehmet Kenan Kanburoglu, Jenna Ibrahim, Prakesh S Shah, Adel Mohamed

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammed EllebanyDepartment of Pediatrics, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0009-0007-8749-7601
Kamini RaghuramDepartment of Pediatrics, University of Toronto, Toronto, ON, Canada.
Mehmet Kenan KanburogluDepartment of Pediatrics, University of Toronto, Toronto, ON, Canada.
Jenna IbrahimDepartment of Pediatrics, Sinai Health System, Toronto, ON, Canada.
Prakesh S ShahDepartment of Pediatrics, University of Toronto, Toronto, ON, Canada.
Adel MohamedDepartment of Pediatrics, University of Toronto, Toronto, ON, Canada. Adel.mohamed@sinaihealth.ca.ORCID http://orcid.org/0000-0001-8031-6627

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare neurodevelopmental outcomes at 18-30 months corrected age (CA) in infants born <29 weeks' gestation cared for in single-family room (SFR) versus open-bay NICUs.

methodsIn this retrospective cohort study, infants born <29 weeks' gestation were admitted to a tertiary NICU that transitioned from an open-bay to an SFR design. Two eras were compared: open-bay (2010-2014) and SFR (2015-2019). The primary outcome was significant neurodevelopmental impairment (sNDI) at 18-30 months CA. Multivariable regression adjusted for potential confounders.

resultsOf 1589 eligible infants, 1017 completed follow-up (471 open-bay, 546 SFR). Infants in SFRs had lower odds of sNDI (unadjusted OR 0.67; 95% CI, 0.48-0.94; adjusted OR 0.51; 95% CI, 0.34-0.76). The open-bay group also had higher rates of hearing loss requiring amplification, retinopathy of prematurity, and mortality before discharge.

conclusionsCare in SFR NICUs was associated with improved neurodevelopmental outcomes and fewer complications compared with open-bay care.

Indexed as

Hospital Design and ConstructionInfant, Extremely PrematureInfant, PrematureIntensive Care Units, NeonatalNeurodevelopmental DisordersChild, PreschoolFemaleGestational AgeHumansInfantInfant, NewbornMaleRetrospective Studies

Identifiers

PMID41073768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.