Evidence map›Paper›PMID 41073677›Full record

ArticleInternational journal of legal medicine2026

Post-mortem fundus examination after sudden unexpected death in infancy (SUDI): can we do better? a study based on the French SUDI registry.

Romain Provost, Jean- Baptiste Ducloyer, Caroline Rambaud, Christele Gras-LeGuen, Renaud Clement, Sophie T Brouard, Audrey Farrugia, Mathilde Ducloyer

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In one paragraph

Article in International journal of legal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Romain ProvostForensic department, Nantes University, CHU de Nantes, 30 bd Jean Monnet, Nantes, 44000-, France.ORCID http://orcid.org/0009-0001-3563-0286
Jean- Baptiste DucloyerOphthalmology department, Nantes University, CHU de Nantes, Nantes, 44000, France.ORCID http://orcid.org/0000-0002-1306-1908
Caroline RambaudDepartment of Pathology and Forensic Medicine, AP-HP University Hospital Raymond Poincaré, University Paris-Saclay, Garches, 92380, France.ORCID http://orcid.org/0000-0003-1443-7337
Christele Gras-LeGuenDepartment of Paediatrics, Nantes University, CHU de Nantes, Nantes, 44000, France.
Renaud ClementForensic department, Nantes University, CHU de Nantes, 30 bd Jean Monnet, Nantes, 44000-, France.
Sophie T BrouardCentre for Research in Epidemiology and Statistics, Université Paris Cité, Inserm, Paris, France.ORCID http://orcid.org/0000-0003-0401-7507
Audrey FarrugiaInstitute of Legal Medicine, Hospital of Strasbourg, University of Strasbourg, 11, rue Humann, Strasbourg Cedex, 67085, France.ORCID http://orcid.org/0000-0002-4453-1618
Mathilde DucloyerForensic department, Nantes University, CHU de Nantes, 30 bd Jean Monnet, Nantes, 44000-, France. mathilde.ducloyer@chu-nantes.fr.ORCID http://orcid.org/0000-0003-1116-4943

Funding

INSERM INSERMMSDAVENIR MSDAVENIRParent associations (SA VIE, Naitre et vivre, Les Rires d'Anna) Parent associations (SA VIE, Naitre et vivre, Les Rires d'Anna)Sanofi Pasteur Sanofi PasteurSanté Publique France Santé Publique France
6 · The paper itself

Abstract

backgroundFundus examination is crucial to assess retinal haemorrhages after sudden unexpected death in infancy (SUDI), to rule out fatal abusive head trauma.

objectiveTo determine how many SUDI cases in France underwent a fundus examination, and to identify factors associated with its completion.

methodChildren who died from SUDI included in the French SUDI registry were analysed. It was determined whether a fundus examination had been performed and, if so, whether the results showed the presence of retinal haemorrhages. Groups having undergone or not fundus examinations were compared in terms of age at death, gender, perinatal history, need for resuscitation, post-mortem investigations (brain imaging, autopsy), potential prosecutor's intervention, and presence of traumatic injuries. A survey was sent to referral centres to determine whether and how they performed fundus examinations.

resultsOur study included 1,326 cases of SUDI occurring between 2015 and 2022, of which 252 (19%) underwent fundus examinations, with a significant increase from 10 (9.3%) in 2015 to 57 (31.8%) in 2022 (p < 0.001). Significant differences were observed between the groups with and without fundus examination in the number of autopsies (217 [86.8%] vs. 845 [79%]; p = 0.004), and the presence of traumatic injuries (15 [6.4%] vs. 23 [2.3%]; p = 0.003). Retinal haemorrhages were detected in 26 children, and were significantly associated with higher rates of prosecutor's interventions after hospital admission (12 [57.1%] vs. 32 [16.2%]; p < 0.001), cardiac activity resumption (9 [40.9%] vs. 17 [7.9%]; p < 0.001) and traumatic injuries (14 [53.8%] vs. 1 [0.5%]; p < 0.001). Of the 34 centres surveyed, 15 completed the questionnaire, and only 5 reported regularly performing fundus examinations.

conclusionA fundus examination is performed in only 19% of SUDI cases in France. Efforts should be made to generalize this examination to avoid missing out fatal abusive head trauma.

Indexed as

Fundus OculiRetinal HemorrhageSudden Infant DeathAutopsyChild, PreschoolFemaleFranceHumansInfantInfant, NewbornMaleRegistriesAbusive head traumaFundus examinationNational registryPost-mortemRetinal haemorrhagesSudden unexpected death in infancy

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.