Evidence map›Paper›PMID 41073600›Full record

ArticleScientific reports2025

Global burden of six musculoskeletal disorders in women of childbearing age from 1990 to 2021.

Haocheng Du, Shi Li, Zichen Tian, Jingbo Lin, Lin Li, Jinzhu Liu, Weibo Xiao, Lingkang Dong, Xintao Zhang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Systematic review of health challenges experienced by Indian women engaged in informal labor.Journal of occupational medicine and toxicology (London, England) · 2026
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haocheng Du *Department of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, No. 1120, Lianhua Road, Futian District, Shenzhen, Guangdong, China.
Shi Li *First Department of Orthopedics, Huangpu People's Hospital of Zhongshan, Zhongshan, China.
Zichen TianDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, No. 1120, Lianhua Road, Futian District, Shenzhen, Guangdong, China.
Jingbo LinFirst Department of Orthopedics, Huangpu People's Hospital of Zhongshan, Zhongshan, China.
Lin LiDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, No. 1120, Lianhua Road, Futian District, Shenzhen, Guangdong, China.
Jinzhu LiuDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, No. 1120, Lianhua Road, Futian District, Shenzhen, Guangdong, China.
Weibo XiaoDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, No. 1120, Lianhua Road, Futian District, Shenzhen, Guangdong, China.
Lingkang DongDepartment of Otolaryngology Head and Neck Surgery, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 600 Yishan Road, Xuhui District, Shanghai, 200030, China. donglingkang@sjtu.edu.cn.
Xintao ZhangDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, No. 1120, Lianhua Road, Futian District, Shenzhen, Guangdong, China. zhangxintao@sina.com.

Funding

National Natural Science Foundation of China No.82272568Sanming Project of Medicine in Shenzen Municipality No.SZSM202211019
6 · The paper itself

Abstract

Women of childbearing age (WCBA) are a high-risk group for musculoskeletal (MSK) disorders and face significant challenges. A comprehensive analysis is needed to understand the impacts and develop suitable strategies. Detailed data on MSK disorders in WCBA over the past 32 years, including rheumatoid arthritis (RA), osteoarthritis (OA), low back pain (LBP), neck pain (NP), gout, and other musculoskeletal disorders (OMSKDs), were collected from the Global Burden of Disease database (GBD2021). The burden of these diseases and trends were assessed using prevalence, disability-adjusted life years (DALYs), the Socio-Demographic Index (SDI), and estimated annual percentage changes , with forecasts made up to 2050.From 1990 to 2021, among WCBA, the number of patients with MSK disorders increased from 245,428,271 to 401,422,090. The rate of increase in prevalence was the greatest in middle SDI regions, while high SDI regions bear the highest age-standardized DALYs rate. The conditions with the most significant increase in Age-Standardized Prevalence Rate are ranked as OA, gout, OMSKDs, RA, and NP, while LBP remained relatively unchanged. The ARIMA model forecasts that the number of cases will further rise, and it is estimated that approximately 500 million WCBA will be affected by MSK diseases by 2050. The contributions of obesity and renal dysfunction to the burden of MSK disorders will further increase.WCBA face a significant burden from MSK disorders, and this burden is forecast to increase further. There is an urgent need to invest more in medical resources to manage MSK conditions in WCBA. Focus on the significant increase in specific MSK disorders and controlling modifiable risk factors is crucial.

Indexed as

Global Burden of DiseaseMusculoskeletal DiseasesAdolescentAdultCost of IllnessDisability-Adjusted Life YearsFemaleGlobal HealthHumansMiddle AgedOsteoarthritisPrevalenceYoung AdultAge-standardized prevalence rate (ASPR)Estimated annual percentage change (EAPC)Global burden of disease (GBD)Musculoskeletal (MSK) disordersWomen of childbearing age (WCBA)

Identifiers

PMID41073600
PMCPMC12514240

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.