Evidence map›Paper›PMID 41073591›Full record

ArticleScientific reports2025

Modifying effects of PM

Weeberb J Requia, Heresh Amini, Paulo Hilario Nascimento Saldiva

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Air Pollution and Brain Tumors in Children. A Systematic Review.Current environmental health reports · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Weeberb J RequiaCenter for Environment and Public Health Studies, School of Public Policy and Government, Fundação Getúlio Vargas Brasília, Distrito Federal, Brazil. weeberb.requia@fgv.br.
Heresh AminiDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Paulo Hilario Nascimento SaldivaDepartment of Pathology, School of Medicine, University of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extreme heat is a critical public health threat, particularly in low- and middle-income countries. While its direct health impacts are well documented, less is known about how air pollution modifies heat-related risks. We analyzed daily hospital admissions for circulatory and respiratory diseases in Brazil (2008-2018), combined with high-resolution temperature and pollution (PM₂.₅ and O₃) data. Using generalized additive models and random-effects meta-analysis, we found that PM₂.₅ consistently amplified the effect of heat on respiratory admissions, with a 20.1% increase in risk under high PM₂.₅ conditions (95% CI 4.8-35.4%). In contrast, O₃ showed heterogeneous effects, including a national-level protective association at high concentrations (- 7.6%, 95% CI - 9.6 to - 5.6%). Regional analyses revealed stronger interactions in the North and Southeast. These findings indicate that PM₂.₅ exacerbates, and O₃ variably modifies, heat-related hospitalizations in Brazil, underscoring the need for regionally tailored adaptation and air quality policies.

Indexed as

Air PollutantsAir PollutionCardiovascular DiseasesHospitalizationHot TemperatureOzoneParticulate MatterRespiratory Tract DiseasesBrazilHumansAir PollutantsOzoneParticulate MatterAir pollutionClimateHeatHospital admissions riskSynergetic effect

Identifiers

PMID41073591
PMCPMC12514149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.