Evidence map›Paper›PMID 41073546›Full record

ArticlePediatric research2026

Outcomes of preterm infants stabilized with flow-inflating bag or T-piece resuscitator at birth-a Canadian neonatal network cohort study.

Melanie Shaker, Jennifer Toye, Eugene Ng, Ruben Alvaro, Ayman Sheta, Deepak Louis, Joseph Y Ting, Marc Beltempo, Georg M Schmölzer, Canadian Neonatal Network

Abstract readMulticenter StudyComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Melanie ShakerCentre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, AB, Canada.
Jennifer ToyeDepartment of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Eugene NgDepartment of Paediatrics, University of Toronto, Ontario, Canada.
Ruben AlvaroDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.
Ayman ShetaDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.
Deepak LouisDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.
Joseph Y TingDepartment of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Marc BeltempoDepartment of Pediatrics, McGill University, Montreal, Quebec, Canada.
Georg M SchmölzerCentre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, AB, Canada. georg.schmoelzer@me.com.ORCID http://orcid.org/0000-0001-9798-2415
Canadian Neonatal Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the outcomes of premature infants stabilized in the delivery room using either the T-piece resuscitator (TPR) or flow-inflating bag (FIB). DESIGN/

methodsData from five participating level III NICUs within the Canadian Neonatal Network were reviewed. Infants born between 24

resultsOf the 2007 infants admitted to participating sites, 426 were excluded, leaving 1581 who met the inclusion criteria. The primary outcome occurred in 367/745 (49%) infants with the FIB and in 438/836 (52%) infants with the TPR (adjusted OR = 0.87; 95% CI 0.44 to 1.71). There was no association between TPR or FIB with the individual components of the composite outcome (death, BPD, and severe neurological injury).

conclusionsThere were no significant differences in the outcomes of preterm infants stabilized in the delivery room with TPR compared to FIB. IMPACT: No significant difference in the composite outcome (death, bronchopulmonary dysplasia (BPD), and severe neurological injury) between a flow-inflating bag (FIB) or a T-piece resuscitator (TPR) for respiratory support at birth. Large real-world analyses comparing TPR and FIB in clinical settings. Respiratory support with either device resulted in no statistically different key clinical outcomes. There was no impact on mechanical ventilation or major morbidities with either device. This emphasizes the importance of provider experience and consistent device use over the choice of resuscitation device.

Indexed as

Infant, PrematureRespiration, ArtificialResuscitationBronchopulmonary DysplasiaCanadaCohort StudiesFemaleGestational AgeHumansInfant, NewbornIntensive Care Units, NeonatalLogistic ModelsMaleTreatment Outcome

Identifiers

PMID41073546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.