ArticleNeuroradiology2025
Lumbar vertebral degenerative and stenosis changes in parkinson's disease: A comparative Cross-sectional study.
Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Is bilateral laminectomy and fusion superior to total laminectomy and fusion in two-level lumbar spinal stenosis?Frontiers in surgery · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLumbar spinal degenerative and stenotic changes in Parkinson's disease (PD) may contribute to limitations in physical activity, resulting in a worsened disease course. The pattern of lumbar spine degeneration and stenosis, the aim of the present study, remains largely unexplored.
methodsThis study included 82 people with PD (PwPD) and 98 age-matched control subjects (CS). Degenerative changes (disc and facet joint degeneration) and stenotic changes (foraminal and central canal stenosis) were assessed using established grading systems.
resultsDisk degeneration at all levels, facet joint degeneration at L3-L4 and foraminal stenotic changes mostly at L1-L4 and beneath L4 levels, were significantly correlated with PD progression (medium strength). PwPD exhibited significantly lower scores for facet joint degeneration and foraminal stenosis compared to CS; however, selecting the CS from subjects with potential lumbar pathologies limits the robustness of this conclusion. A significant positive correlation between the overall extent of degeneration and the total score of stenosis was observed in both groups. This positive correlation was represented in a regression model for both groups. The rate of degenerative and stenotic changes positively influences one another in a pattern of increasing rates, which was stronger in PwPD compared to CS.
conclusionsOur findings indicate that PwPD may show lower levels of certain degenerative and stenotic changes; however, the interaction between these factors was more pronounced in these individuals compared to the controls. Future prospective studies can evaluate these findings and assess the role of PD scoring systems in lumbar MRI findings.
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