ArticleScientific reports2025
MdHSFA2 enhances heat stress tolerance through promoting the MdGolS4 transcription in apple.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Advances in Physiological and Molecular Mechanisms of Heat Stress in Apple and Pear.Plants (Basel, Switzerland) · 2026Review
- From Perception to Adaptation: A Comparative Study of Plant Regulatory Networks in Response to Heat and Waterlogging Stress.Plants (Basel, Switzerland) · 2026Review
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Authors and funding
8 authors.
Funding
Abstract
With global climate change, extremely high temperatures are occurring frequently during summer, seriously affecting development of the apple industry. Heat-shock factors (HSFs) are important signaling proteins for plants to respond to heat stress. However, research on the effects of the apple HSF gene on the regulation of heat-stress tolerance is lacking. In this study, we analyzed the expression and function of MdHSFA2, an HSF, in apples. The MdHSFA2 expression level significantly increased under heat treatment, and Arabidopsis overexpressing MdHSFA2 showed significantly higher tolerance than that in the WT plants. In addition, we found that apple MdGolS4/6 had the highest expression levels among the eight MdGolSs under heat treatment. Using electrophoretic mobility shift (EMSA) and dual-luciferase assays, we found that MdHSFA2 could directly bind to the MdGols4 promoter region thereby promoting transcription. MdGolS4 overexpression in Arabidopsis enhances heat-stress tolerance. Our findings suggest that MdHSFA2 directly promotes MdGolS4 transcription, thereby enhancing heat-stress tolerance in apples. These results enhance our understanding of heat-stress tolerance mechanisms.
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