Evidence map›Paper›PMID 41073450›Full record

ArticleScientific data2025

A high-resolution temporal transcriptomic and imaging dataset of porcine wound healing.

Ksenia Zlobina, Hsin-Ya Yang, Manasa Kesapragada, Fan Lu, Anthony Gallegos, Guillermo Villa-Martinez, Moyasar A Alhamo, Kan Zhu, Cynthia Recendez, Craig Collins and 6 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Porcine Wound Models: The Gold Standard for Translational Research in Cutaneous Healing.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ksenia ZlobinaUniversity of California Santa Cruz, Department of Applied Mathematics, Santa Cruz, 95064, USA.ORCID 0000-0001-6592-0965
Hsin-Ya YangUniversity of California Davis, Department of Dermatology, Sacramento, 95817, USA.ORCID 0000-0002-5325-494X
Manasa KesapragadaUniversity of California Santa Cruz, Department of Applied Mathematics, Santa Cruz, 95064, USA.
Fan LuUniversity of California Santa Cruz, Department of Applied Mathematics, Santa Cruz, 95064, USA.
Anthony GallegosUniversity of California Davis, Department of Dermatology, Sacramento, 95817, USA.
Guillermo Villa-MartinezUniversity of California Davis, Department of Dermatology, Sacramento, 95817, USA.
Moyasar A AlhamoUniversity of California Davis, Department of Dermatology, Sacramento, 95817, USA.
Kan ZhuUniversity of California Davis, Department of Ophthalmology and Vision Science, Sacramento, 95817, USA.
Cynthia RecendezUniversity of California Davis, Department of Ophthalmology and Vision Science, Sacramento, 95817, USA.
Craig CollinsUniversity of California Davis, Department of Dermatology, Sacramento, 95817, USA.
Marco RolandiUniversity of California Santa Cruz, Department of Electrical Engineering, Santa Cruz, 95064, USA.
Athena SoulikaUniversity of California Davis, Department of Dermatology, Sacramento, 95817, USA.
Elham AslankoohiUniversity of California Santa Cruz, Department of Electrical Engineering, Santa Cruz, 95064, USA.
Min ZhaoUniversity of California Davis, Department of Ophthalmology and Vision Science, Sacramento, 95817, USA.ORCID 0000-0002-2500-3035
Marcella GomezUniversity of California Santa Cruz, Department of Applied Mathematics, Santa Cruz, 95064, USA. mgomez26@ucsc.edu.
R Rivkah IsseroffUniversity of California Davis, Department of Dermatology, Sacramento, 95817, USA. rrisseroff@ucdavis.edu.

Funding

5-Lipoxygenase exerts dual and opposing functions during the wound healing processR01GM135279 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SOULIKA, ATHENA · 2020 to 2023
$1.5M
NIGMS NIH HHS R01 GM135279United States Department of Defense | Defense Advanced Research Projects Agency (DARPA) DC20AC00003
6 · The paper itself

Abstract

Wound healing is a dynamic process involving various cell types. Collecting samples from healing wounds and investigating their transcriptomics can provide deeper insights into the underlying processes. In recent years, several experiments have been conducted to gather transcriptomic data from wounds in both humans and animals. However, the temporal resolution of such data often does not adequately match the dynamics of the process, and spatial aspects are frequently overlooked. Here, we present a dataset collected from an experiment on wound healing in pigs, including gene expression profiles at the wound edge and center, and photographs of the wounds. Photographs provide non-invasive data, and advancements in image analysis using artificial intelligence methods are actively being integrated into medical practice. Being collected within the same experiment, these comprehensive data can aid in building intelligent wound diagnostics and treatment algorithms.

Indexed as

TranscriptomeWound HealingAnimalsGene Expression ProfilingImage Processing, Computer-AssistedSwine

Identifiers

PMID41073450
PMCPMC12514037

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.