ArticleTranslational psychiatry2025
Global, regional, and national burden of mental disorders among adolescents and young adults, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
Article in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- National prevalence and sociodemographic correlates of potential depression, anxiety, and suicidality among the young population in Kazakhstan: a national population-based study.BMC psychology · 2026Article
- Embodied pathways of recovery: interoceptive change and the reduction of depressive symptoms following Tai Chi in women aged 40-55 years.Archives of women's mental health · 2026Article
- Burden of anxiety disorders in Colombia: subnational DALY estimates and territorial inequalities, 2016-2022.Population health metrics · 2026Article
- The Transition to Mental Health Services From the Perspectives of Neurodivergent Young People, Caregivers and Mental Health Professionals: A Constructivist Grounded Theory Approach.Journal of autism and developmental disorders · 2026Article
- Health Care Professionals' Perspectives on Conversational Mental Health Chatbots: Protocol for a Systematic Review.JMIR research protocols · 2026Article
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- Adverse childhood experiences, resilience and mental health among young people aged 16-29 years in Nepal: a population-based household survey (2025).The Lancet regional health. Southeast Asia · 2026Article
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- Effects of Digital Nature Interventions on Positive Psychological Outcomes: A Scoping Review.Behavioral sciences (Basel, Switzerland) · 2026Review
- A bibliometric analysis of global research trends and emerging hotspots on suicide and depression among children and adolescents.Discover mental health · 2026Review
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- EEG Functional Connectivity Associated With Antidepressant Response to Transcutaneous Electrical Cranial-Auricular Acupoint Stimulation.CNS neuroscience & therapeutics · 2026Article
- The Many Faces of Stress: Preliminary Validation of a Remote Photoplethysmography-Based Tool for Psychophysiological Stress and Emotional Distress Monitoring.Healthcare (Basel, Switzerland) · 2026Article
- Symptoms of depression, suicidal ideation, and personality traits in a sample of medical students: a cross-sectional study.BMC psychiatry · 2026Article
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- The DSM needs more than revision: five blind spots and a case for dialogical redesign.Psychological medicine · 2026Article
- Debate: Young people are living in unprecedented times - too much chaos or too little resilience?: No Pain, No Gain? Why articulating distress marks youth resilience.Child and adolescent mental health · 2026Article
- [Research on weighted hypergraph attention neural network for the diagnosis of psychiatric disorders using brain functional connectivity networks].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Article
- Microbial regulation of stress-associated signaling molecules and its role in health and disease.NPJ biofilms and microbiomes · 2026Review
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7 authors.
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Abstract
Mental disorders among adolescents and young adults (ages 10-24) are a significant public health challenge, contributing to long-term morbidity and substantial societal impact. This study analyzes the prevalence, incidence, and years lived with disability (YLDs) of mental disorders in this age group from 1990-2021, with particular attention to the effects of the COVID-19 pandemic during 2019-2021. Using data from the Global Burden of Disease Study 2021, we estimated the prevalence, incidence, and YLDs, along with age-standardized rates (ASR) and 95% uncertainty intervals (95% UIs) for 2021, stratified by sex and age group. Joinpoint regression was employed to calculate annual percentage change (APC) and average annual percentage change (AAPC), along with their corresponding 95% confidence intervals (CIs). In 2021, the global prevalence of mental disorders among adolescents and young adults was 278.98 million (95% UI: 248.61-312.81), with an ASR of 14,764.94 (95% UI: 2804.87-16,908.09). From 2019-2021, there were significant increases in the prevalence, incidence, and YLDs of mental disorders, especially for depressive and anxiety disorders. High-income regions, including North America, Western Europe, and the Asia Pacific, experienced the highest burdens. Globally, the prevalence of mental disorders was higher in males than females among adolescents aged 10-14, but higher in females among those aged 15-24. Joinpoint regression analysis from 1990-2021 revealed an increased burden in depressive disorders, anxiety disorders, bipolar disorder, eating disorders, autism spectrum disorder, conduct disorder, and idiopathic developmental intellectual disability, while decreases were observed in schizophrenia, ADHD, and other mental disorders. This study highlights the significant impact of COVID-19 on the mental health of adolescents and young adults, revealing disparities by region, age, sex, time period, and cohort. It underscores the need for targeted interventions to address the rising mental health burden in this group.
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