ArticleJACC. Case reports2025
Cardiopulmonary Exercise Testing-Guided Optimization of Pacemaker Rate-Response in an Endurance Athlete With Sinus Node Dysfunction.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Exercise Stress Testing in Clinical Cardiology: A Practical Guide to Performance and Interpretation.Journal of clinical medicine · 2026Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundAthletes with a permanent pacemaker for sinus node dysfunction can experience exercise intolerance related to suboptimal rate-response pacing, often isolated to periods of peak or prolonged effort. Nominal pacemaker rate modulation settings do not recapitulate physiological exercise well. CASE SUMMARY: We present a case of a 70-year-old lifelong runner with implanted permanent pacemaker for sinus node dysfunction presenting with exercise intolerance and dyspnea on exertion. A combined maximum effort cardiopulmonary exercise test with device interrogation produced an optimized pacemaker settings profile which resolved his symptoms. DISCUSSION: Highly active patients with sinus node dysfunction depend on rate-response pacing during exercise. Optimized pacemaker function for high intensity sports can relieve symptoms and improve performance. Our case highlights the importance of an athlete-tailored approach combining maximum effort metabolic, exercise, and device testing.
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