ArticleJACC. Case reports2025
Ultrasound-Facilitated, Catheter-Directed Thrombolysis to Treat Transcatheter Pulmonary Valve Frame Thrombosis.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Reply: Management of Transcatheter Pulmonary Valve Thrombosis With Low-Dose, Slow-Infusion Fibrinolytic Therapy.JACC. Case reports · 2026Article
- Management of Transcatheter Pulmonary Valve Thrombosis With Low-Dose, Slow-Infusion Fibrinolytic Therapy.JACC. Case reports · 2026Article
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Authors and funding
3 authors.
Funding
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Abstract
objectiveWe present a patient with tetralogy of Fallot who underwent transcatheter pulmonary valve replacement complicated by elevated pulmonary valve gradients and subvalvular mural thrombus, and was treated using ultrasound-facilitated, catheter-directed thrombolysis. KEY STEPS: Right internal jugular access was obtained, and the EKOS endovascular system was advanced across the pulmonary valve and used to deliver slow infusions of alteplase. We then performed balloon valvuloplasty of the transcatheter pulmonary valve after 48 hours of lysis. POTENTIAL PITFALLS: There is risk for intracranial hemorrhage while receiving prolonged infusions of intravascular lytic therapy; the patient was monitored in the intensive care unit with frequent neurologic examinations and serum coagulation tests. TAKE-HOME MESSAGES: Valve thrombosis is a known complication of transcatheter pulmonary valve replacement, the management of which typically involves either percutaneous valve-in-valve implantation or surgical valve replacement. The novel approach detailed in this report presents an alternative that avoids sternotomy or implanting a second transcatheter valve.
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