Evidence map›Paper›PMID 41072401›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Premorbid Metabolic Syndrome Is Associated with the Hypoinflammatory Phenotype in Acute Respiratory Distress Syndrome and Sepsis.

Avery M Bogart, Sarah N Obeidalla, Rombout B E van Amstel, Olaf Cremer, Lieuwe D J Bos, Brian Bartek, Pratik S Sinha, Carolyn S Calfee, V Eric Kerchberger, Lorraine B Ware and 1 more

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Avery M BogartDepartment of Pathology, Microbiology, and Immunology.ORCID 0000-0002-3912-3177
Sarah N ObeidallaDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Rombout B E van AmstelDepartment of Intensive Care Medicine, Amsterdam University Medical Center, Locatie Amsterdam Medical Center, Amsterdam, the Netherlands.ORCID 0000-0001-9296-8518
Olaf CremerDepartment of Intensive Care Medicine, Amsterdam University Medical Center, Locatie Amsterdam Medical Center, Amsterdam, the Netherlands.
Lieuwe D J BosDepartment of Intensive Care Medicine, Amsterdam University Medical Center, Locatie Amsterdam Medical Center, Amsterdam, the Netherlands.
Brian BartekDivision of Clinical and Translational Research, Department of Anesthesia, Washington University in St Louis, St. Louis, Missouri; and.
Pratik S SinhaDivision of Clinical and Translational Research, Department of Anesthesia, Washington University in St Louis, St. Louis, Missouri; and.
Carolyn S CalfeeDivision of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine and.
V Eric KerchbergerDepartment of Biomedical Informatics, and.ORCID 0000-0002-0342-1965
Lorraine B WareDepartment of Pathology, Microbiology, and Immunology.ORCID 0000-0002-9429-4702
MARS Consortium

Funding

Precision Medicine in Sepsis with Critical IllnessR35GM142992 · NIGMS · WASHINGTON UNIVERSITY · PI Pratik Sinha · 2021 to 2026
$2.4M
Tissue-specific functional genomics in the acute respiratory distress syndromeK01HL157755 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KERCHBERGER, VERN ERIC · 2021 to 2025
$845k
Mechanisms of Cell-Free Hemoglobin-Mediated Injury to the Pulmonary Endothelial Glycocalyx in SepsisF30HL170483 · NHLBI · VANDERBILT UNIVERSITY · PI BOGART, AVERY MAY · 2023 to 2025
$121k
NHLBI NIH HHS F30HL170483NHLBI NIH HHS HL140026NHLBI NIH HHS HL158906NHLBI NIH HHS HL168412NHLBI NIH HHS K01 HL157755NIGMS NIH HHS R35 GM142992
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41072401
PMCPMC12700243

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.