Evidence map›Paper›PMID 41071891›Full record

ArticleScience advances2025

A DNA-containing phase-separated compartment links the nuclear envelope to chromosome axes to promote homolog pairing in

Ruoxi Wang, Yuqi Tian, Libo Liu, Jian-Hua Wang, Li Zhao, Yuanyuan Liu, Feifei Qi, Liangran Zhang, Jun Zhou, Meng-Qiu Dong and 1 more

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruoxi WangCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0000-0002-8417-1987
Yuqi TianCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0009-0005-5118-0165
Libo LiuCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.
Jian-Hua WangNational Institute of Biological Sciences, Beijing 102206, China.ORCID 0000-0002-7546-5449
Li ZhaoCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.
Yuanyuan LiuCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.
Feifei QiCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.
Liangran ZhangCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0000-0002-8550-6742
Jun ZhouCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0000-0003-3131-7804
Meng-Qiu DongNational Institute of Biological Sciences, Beijing 102206, China.ORCID 0000-0002-6094-1182
Jinmin GaoCenter for Cell Structure and Function, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0000-0002-5894-6515

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Homologous chromosome pairing is a critical prerequisite for successful meiosis, yet the molecular mechanisms underlying this process remain elusive. In

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsChromosome PairingChromosomesDNANuclear EnvelopeAnimalsCell Cycle ProteinsChromatinMeiosisProtein BindingCaenorhabditis elegans ProteinsCell Cycle ProteinsChromatinDNAHIM-8 protein, C elegans

Identifiers

PMID41071891
PMCPMC12513456

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.