Evidence map›Paper›PMID 41071656›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Natural history of liver fluke infection underpins epidemiological patterns of biliary cancer.

Thomas Crellen, Francesca Vita, Chiara Braconi, Paiboon Sithithaworn, T Déirdre Hollingsworth

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas CrellenSaw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore.ORCID 0000-0003-2934-1063
Francesca VitaSchool of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Glasgow G61 1QH, United Kingdom.
Chiara BraconiSchool of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Glasgow G61 1QH, United Kingdom.
Paiboon SithithawornDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-9480-1778
T Déirdre HollingsworthBig Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7LF, United Kingdom.

Funding

European Cooperation in Science and Technology (COST) CA18122European Cooperation in Science and Technology (COST) CA22125Wellcome TrustWellcome Trust (WT) 215919/B/19/Z
6 · The paper itself

Abstract

Pathogens are major drivers of cancer globally and the processes of infection and carcinogenesis unfold over decades making them difficult to observe in human or natural populations. We investigate these hidden dynamics for the foodborne trematode

Indexed as

Bile Duct NeoplasmsBiliary Tract NeoplasmsCholangiocarcinomaOpisthorchiasisOpisthorchisAdultAnimalsFemaleHumansMaleMiddle AgedThailandcancer evolutionepidemiologyneglected tropical diseasesparasitology

Identifiers

PMID41071656
PMCPMC12541340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.