Evidence map›Paper›PMID 41071649›Full record

ArticleBioinformatics (Oxford, England)2025

STCRpy: a software suite for T-cell receptor structure parsing, interaction profiling, and machine learning dataset preparation.

Nele P Quast, Charlotte M Deane, Matthew I J Raybould

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nele P QuastOxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.ORCID 0009-0002-7460-8572
Charlotte M DeaneOxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.ORCID 0000-0003-1388-2252
Matthew I J RaybouldOxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.ORCID 0000-0002-5663-5297

Funding

Engineering and Physical Sciences Research CouncilEPSRC EP/S024093/1
6 · The paper itself

Abstract

summaryComputational methods to guide early-stage TCR drug discovery and TCR repertoire informatics currently under-utilize solved and predicted structure data. Here, we streamline use of these data through an open-source python package for high-throughput TCR structure handling and analysis (STCRpy), facilitating analyses such as TCR:peptide-MHC complex orientation calculation/scoring, root-mean-square-distance evaluation, interaction profiling, and machine learning dataset curation. AVAILABILITY AND IMPLEMENTATION: Freely available as a Python package at https://github.com/oxpig/STCRpy.

Indexed as

Machine LearningReceptors, Antigen, T-CellSoftwareComputational BiologyHumansReceptors, Antigen, T-Cell

Identifiers

PMID41071649
PMCPMC12574948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.