ArticleDiscover oncology2025
B cell-associated research in non-small cell lung cancer: a bibliometric analysis of current landscapes and future directions.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Bibliometric Analysis of Gut Microbiota and Hepatocellular Carcinoma: Research Trends and Frontiers.Journal of hepatocellular carcinoma · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundRecent years have witnessed growing interest in the interplay between B cells and non-small cell lung cancer (NSCLC) amid deepening investigations into cancer immunotherapy. B cells play pivotal roles in immunotherapeutic contexts by modulating tumor progression through immunoglobulin secretion, T-cell response activation, and direct tumoricidal activity. In this study, we employ bibliometric techniques to analyze research hotspots and evolutionary trends in NSCLC-associated B-cell investigations, aiming to inform future directions in this burgeoning field.
methodsWe conducted a systematic retrieval of peer-reviewed documents (original articles, reviews, editorials) from the Web of Science Core Collection (2004-2024). Bibliometric networks were constructed using CiteSpace 6.1.R6 and VOSviewer 1.6.18. With temporal productivity patterns analyzed through Microsoft Excel 2021.
resultsThis study analyzed 437 publications from 1,677 institutions across 156 countries/regions, encompassing 3,360 researchers. Annual publications showed sustained growth (2004-2021) followed by decline (2022-2024). China demonstrated highest productivity (n = 169), the United States dominated total citations (6,943). Keyword and highly cited literature analyses primarily focused on elucidating B cell heterogeneity and tertiary lymphoid structures, deciphering B cell-T cell interaction mechanisms, and exploring synergistic applications of B cells with other immunotherapeutic approaches.
conclusionThis study utilizes bibliometric analysis to explore research hotspots and developmental trends in B - cell - related studies of non - small cell lung cancer (NSCLC) over the past two decades. By elucidating the changing research landscape, this work aims to enhance researchers' comprehension of the immunological milieu and advancements in NSCLC immunotherapy, promote scientific advancement in this field, and provide directional guidance for future research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.