Evidence map›Paper›PMID 41071351›Full record

ArticleArchives of orthopaedic and trauma surgery2025

Clinical and radiological 2-year results after autologous shaver-based minced cartilage implantation for cartilage lesions of the knee.

Stefan Pohl, Matthias Mühler, Alexander Zimmerer, Janosch Schoon, Georgi I Wassilew, Sebastian Gebhardt

Abstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stefan PohlCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-SauerbruchStraße, 17475, Greifswald, Germany.
Matthias MühlerInstitute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
Alexander ZimmererCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-SauerbruchStraße, 17475, Greifswald, Germany.
Janosch SchoonCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-SauerbruchStraße, 17475, Greifswald, Germany.
Georgi I WassilewCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-SauerbruchStraße, 17475, Greifswald, Germany.
Sebastian GebhardtCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Ferdinand-SauerbruchStraße, 17475, Greifswald, Germany. Sebastian.Gebhardt@kkh-demmin.de.ORCID http://orcid.org/0000-0001-9332-1927

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe autologous shaver-based minced cartilage implantation is increasingly used for the treatment of focal cartilage lesions of the knee. However, in the absence of randomised controlled studies on this specific technique, its efficacy in comparison to established cartilage repair methods is a matter of debate. MATERIALS AND

methodsEleven patients (12 cases) were prospectively included in this study. One female patient was excluded due to conversion to total knee arthroplasty. All 11 analysed cases (8 females, 3 males; mean age: 42.7 ± 11.8 years, body mass index (BMI): 29.6 ± 6.1 kg/m

resultsStatistically significant improvement at 24 months follow up was observed for pain relief, as documented by the VAS and KOOS total, as well as the KOOS subsccores pain and activities of daily living. Out of 11 cases the MCID was reached in 9 cases considering VAS, 5 cases considering IKDC, 7 cases considering KOOS total and sport, 6 cases considering quality of life and 5 cases considering symptoms and activities of daily living. The postoperative mean MOCART score was 51.4 ± 22.0 and the mean T2-Index was 0.72 ± 0.18. In 3 of 11 postoperative MRIs no transplanted cartilage was observed.

conclusionTreatment of focal cartilage lesions at the knee with the autologous shaver-based minced cartilage implantation provided pain relief and improved function at 2 years follow up. Radiologic results indicated that on average the transplanted cartilage was different from hyaline cartilage, however, according to the T2-Index, in two cases the transplanted cartilage exhibited qualitative MR morphological properties similar to hyaline cartilage.

Indexed as

Cartilage, ArticularKnee InjuriesKnee JointAdultFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesTransplantation, AutologousTreatment Outcome

Identifiers

PMID41071351
PMCPMC12513964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.