Trial reportLasers in medical science2025
Comparative efficacy and safety of 577-nm diode laser versus 1064-nm Nd: YAG laser for inflammatory acne vulgaris: a split-face randomized study.
Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acne vulgaris is a common inflammatory skin disorder with physical and psychosocial impact. Laser therapies offer targeted, non-pharmacologic treatment options. We aimed to compare the efficacy and safety of the 577-nm diode laser versus the 1064-nm Nd: YAG laser in treating inflammatory acne vulgaris. In this prospective, split-face randomized trial, 52 patients underwent three sessions of laser treatment at two-week intervals. One side of the face was treated with a 577-nm diode laser and the other with a 1064-nm Nd: YAG laser. Outcomes included inflammatory lesion counts, Acne Severity Index (ASI), patient satisfaction, and adverse effects. Both lasers significantly reduced inflammatory lesions (p < 0.001), with no significant difference between groups (p > 0.05). Excellent ASI response was observed in 26.9% (diode) and 28.8% (Nd: YAG) treated sides. Satisfaction scores were comparable (2.5 ± 0.6 vs. 2.6 ± 0.5; p = 0.59). Adverse events were mild and transient, with no serious complications. The 577-nm diode and 1064-nm Nd: YAG lasers are equally effective and well-tolerated for inflammatory acne, offering safe alternatives to conventional therapies.
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