ArticleSurgery today2026
The impact of oral frailty on chronic limb-threatening ischemia: the masseter muscle area as a predictive marker for pneumonia and survival.
Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePatients with chronic limb-threatening ischemia (CLTI) often have multiple comorbidities and a poor prognosis. This study analyzes the association between the masseter muscle area (MMA), pneumonia, and the overall survival of CLTI patients older than 65 years.
methodsThe subjects of this retrospectively analysis were 54 consecutive patients with CLTI. The MMA was assessed by computed tomography (CT) as the largest cross-sectional area of the masseter muscle, located 2 cm below the zygomatic arch, at diagnosis. Pneumonia was defined as radiographic infiltrates with fever or leukocytosis, requiring hospitalization within 1 year after diagnosis. The endpoints were pneumonia incidence and survival.
resultsPneumonia developed within 1 year in 22 patients (41%). Multivariate analysis revealed significant associations with male gender (OR: 6.24, p = 0.048), history of pneumonia (OR: 5.21, p = 0.048), and low MMA (OR: 4.46, p = 0.045). Survival rates were 72% at 1 year, 35% at 5 years, and 24% at 10 years. Low MMA was the only significant predictor of overall survival (p < 0.001).
conclusionThe MMA was significantly associated with pneumonia and the poor prognosis of CLTI patients over the age of 65 years. As an indicator of oral frailty, the MMA may serve as a useful prognostic marker to guide treatment planning and interventions in this high-risk population.
Indexed as
Identifiers
41071323What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.