Evidence map›Paper›PMID 41071204›Full record

ArticleJournal of neurology2025

Seizures after decompressive surgery for cerebral venous thrombosis.

Mayte Sanchez van Kammen, Sanjit Aaron, Jorge M Ferreira, Patrícia Canhão, Adriana B Conforto, Antonio Arauz, Marta Carvalho, Jaime Masjuan, Vijay K Sharma, Jukka Putaala and 12 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Mayte Sanchez van KammenDepartment of Neurology, Amsterdam University Medical Centers, University of Amsterdam, AMC, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. m.sanchezvankammen@amsterdamumc.nl.ORCID http://orcid.org/0000-0001-5614-9689
Sanjit AaronNeurology Unit, Department of Neurological Sciences, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Jorge M FerreiraServiço de Neurologia, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.ORCID http://orcid.org/0000-0001-7138-7597
Patrícia CanhãoServiço de Neurologia, Departamento de Neurociências E Saúde Mental, Unidade Local de Saúde Santa Maria, Lisbon, Portugal.ORCID http://orcid.org/0000-0003-3816-0416
Adriana B ConfortoHospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-7869-3490
Antonio ArauzStroke Clinic, Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-3340-4138
Marta CarvalhoServiço de Neurologia, Departamento de Neurociências Clínicas E Saúde Mental, Unidade Local de Saúde São João, Faculdade de Medicina da Universidade Do Porto, Porto, Portugal.ORCID http://orcid.org/0000-0001-6972-9287
Jaime MasjuanServicio de Neurología, Departamento de Medicina, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá. Red INVICTUS, Madrid, Spain.ORCID http://orcid.org/0000-0003-1329-0943
Vijay K SharmaDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0002-8976-5696
Jukka PutaalaDepartment of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0002-6630-6104
Maarten UyttenboogaartDepartment of Neurology and Medical Imaging Center University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-6934-4456
David J WerringStroke Research Centre, UCL Queen Square Institute of Neurology, London, UK.ORCID http://orcid.org/0000-0003-2074-1861
Rodrigo BazanFaculdade de Medicina Campus de Botucatu, Universidade Estadual Paulista Julio de Mesquita Filho, Botucatu, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-3872-308X
Sandeep MohindraDepartment of Neurosurgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.ORCID http://orcid.org/0000-0002-4629-4900
Jochen WeberDepartment of Neurosurgery, Steinenberg Clinic, Reutlingen, Germany.ORCID http://orcid.org/0009-0008-5891-4688
Bert A CoertDepartment of Neurosurgery, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-3277-031X
Prabhu KirubakaranNeurology Unit, Department of Neurological Sciences, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Pankaj SinghNeurology Unit, Department of Neurological Sciences, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Diana Aguiar de SousaCentro de Estudos Egas Moniz, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.ORCID http://orcid.org/0000-0002-6702-7924
Jonathan M CoutinhoDepartment of Neurology, Amsterdam University Medical Centers, University of Amsterdam, AMC, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-8284-982X
José M FerroCentro de Estudos Egas Moniz, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.ORCID http://orcid.org/0000-0002-2343-9097
DECOMPRESS-2 Study Group

Funding

Jan Wouter ten Cate Prize 2021
6 · The paper itself

Abstract

introductionThe incidence and outcomes of seizures among patients with severe cerebral venous thrombosis treated with decompressive surgery are unknown as are potential predictors of seizures in these patients. PATIENTS AND

methodsWe report data from a multicenter, consecutive cohort including patients with cerebral venous thrombosis treated with decompressive surgery from 15 hospitals in 10 different countries between December 2011 and December 2019. We analyzed the cumulative incidence of seizures within one year after decompressive surgery and performed an exploratory analysis of potential factors associated with the incidence of post-surgery seizures, adjusted for competing mortality risk.

resultsOf 116 included patients (median age 38 years [IQR 27-46], 68% female), 26 (22%) had seizures within one year after decompressive surgery. The mortality-adjusted cumulative one-year incidence of a first seizure after surgery was 23% (95% CI 16-31). Only aphasia at presentation predicted post-surgery seizures. Among patients who had a post-surgery seizure, the first seizure occurred despite active treatment with anti-seizure medications in 83% of patients. Recurrent seizures within the first year after surgery were reported in 63% of patients. DISCUSSION AND

conclusionDespite extensive use of anti-seizure medications, in patients with cerebral venous thrombosis treated with decompressive surgery the rate of seizures was 23% (95% CI 16-31) within one year after surgery. Of the patients who had a seizure after surgery, 63% had a recurrent seizure within the first year post-surgery.

Indexed as

Decompression, SurgicalDecompressive CraniectomyIntracranial ThrombosisPostoperative ComplicationsSeizuresVenous ThrombosisAdultCohort StudiesFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesDecompressive craniectomyIntracranial sinus thrombosisPrognosisSeizures

Identifiers

PMID41071204
PMCPMC12513892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.