SynthesisLasers in medical science2025
Efficacy of low-level laser as an adjunctive therapy in root canal treatment and retreatment: an umbrella review.
Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
This study aimed to evaluate and synthesize evidence from systematic reviews investigating the efficacy of low-level laser therapy (LLLT) as an adjunct to endodontic treatment in reducing postoperative pain, microbial load, and promoting apical healing. A comprehensive search of electronic databases (PubMed, Embase, Web of Science, Cochrane Library, Google Scholar) was conducted from February 2024 to March 2025, to retrieve systematic reviews that evaluate the efficacy of LLLT as an adjunct to endodontic treatment in reducing postoperative pain, microbial load, and promoting apical healing. Two independent authors selected the studies, extracted relevant data, and assessed the individual risk of bias and methodological quality using the ROBIS and AMSTAR-2 tools, respectively. The electronic search identified 280 records, 18 of which met the eligibility criteria and were included in the qualitative synthesis. The studies were published between 2014 and 2024. Only six reviews demonstrated a low risk of bias, and two were classified as having high methodological quality. Most systematic reviews indicated that LLLT is effective in reducing the incidence and intensity of postoperative endodontic pain and the microbial load following instrumentation. The studies also highlighted the high heterogeneity, the lack of a standardized protocol for LLLT application, and the low certainty of evidence for the outcomes. LLLT is an important adjunctive therapy in endodontic treatment; however, robust evidence regarding its application protocol is still lacking.
Indexed as
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41071201What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.