Evidence map›Paper›PMID 41071067›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2025

Evaluation of antioxidant and anti-inflammatory potential and

Naveen V Kulkarni, Anaswara S A, Induja S A, Dineshchakravarthy Senthurpandi, Dimitar G Bojilov, Stanimir P Manolov, Iliyan I Ivanov, Jamelah S Al-Otaibi, Y Sheena Mary

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In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Naveen V KulkarniDepartment of Chemistry, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Anaswara S ADepartment of Chemistry, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Induja S ADepartment of Chemistry, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Dineshchakravarthy SenthurpandiCenter of Molecular and Macromolecular Studies, Polish Academy of Sciences, Lodz, Poland.
Dimitar G BojilovDepartment of Organic Chemistry, University of Plovdiv, Plovdiv, Bulgaria.
Stanimir P ManolovDepartment of Organic Chemistry, University of Plovdiv, Plovdiv, Bulgaria.
Iliyan I IvanovDepartment of Organic Chemistry, University of Plovdiv, Plovdiv, Bulgaria.
Jamelah S Al-OtaibiDepartment of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Y Sheena MaryDepartment of Physics, FMNC, University of Kerala, Kollam, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two edaravone derivatives were synthesised and characterised by using several spectral and analytical techniques. The antioxidant activities of these organic compounds were analysed by using HPSA, DPPH and ABTS·+ assays. Anti-inflammatory property of the synthesised derivatives was analysed by evaluating albumin denaturation inhibition abilities. Optical energy band gaps were evaluated using the Tauc plots. Computational method was used to analyse the frontier molecular orbitals of the compounds and MEP surface analysis was used to identify the nucleophilic and electrophilic attacking sites. Owing to the higher antioxidant potential the interaction of the compound

Indexed as

Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsAntipyrineEdaravoneMonophenol MonooxygenaseBacillus megateriumBenzothiazolesBinding SitesBiphenyl CompoundsDose-Response Relationship, DrugMolecular Docking SimulationMolecular StructurePicratesStructure-Activity RelationshipSulfonic Acids1,1-diphenyl-2-picrylhydrazylAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsAntipyrineBenzothiazolesBiphenyl CompoundsEdaravoneMonophenol MonooxygenasePicratesSulfonic Acidsanti-inflammatory compoundsantioxidantsEdaravoneMD simulationtyrosinase binding

Identifiers

PMID41071067
PMCPMC12517414

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.