Evidence map›Paper›PMID 41071054›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Propensity score analysis of stented versus rapid deployment aortic bioprostheses in patients with small aortic annulus.

Giorgia Cibin, Augusto D'Onofrio, Valentina Lombardi, Emma Bergonzoni, Giulia Lorenzoni, Elisa Gastino, Giuseppe Evangelista, Enrico Giuseppe Italiano, Irene Cao, Dario Gregori and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Giorgia CibinDivision of Cardiac Surgery, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.ORCID 0000-0002-2584-2613
Augusto D'OnofrioDivision of Cardiac Surgery, University of Roma "Tor Vergata", Rome 00133, Italy.ORCID 0000-0002-9835-9091
Valentina LombardiDivision of Cardiac Surgery, University of Roma "Tor Vergata", Rome 00133, Italy.
Emma BergonzoniDivision of Cardiac Surgery, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.
Giulia LorenzoniUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.
Elisa GastinoDivision of Cardiac Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Milano 20097, Italy.
Giuseppe EvangelistaDivision of Cardiac Surgery, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.
Enrico Giuseppe ItalianoDivision of Cardiac Surgery, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.
Irene CaoDivision of Cardiac Surgery, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.
Dario GregoriUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.
Chiara TessariDivision of Cardiac Surgery, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.
Gino GerosaDivision of Cardiac Surgery, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova 35128, Italy.ORCID 0000-0002-6261-699X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHaemodynamic studies have demonstrated the excellent performance of rapid deployment (RD) valves. This retrospective single-centre study aimed to compare early and medium-term outcomes of RD bioprostheses versus conventional stented valves in patients with small aortic annuli.

methodsWe included patients who underwent isolated or combined surgical aortic valve replacement (SAVR) with Magna Ease (ME) and Intuity (Edwards Lifesciences, Irvine, CA) sizes 19 and 21 at our institution between June 2016 and March 2022. Follow-up was conducted through scheduled visits and echocardiograms at the study site, or via telephonic interviews with patients and/or referring cardiologists. A propensity score weighting analysis was performed to account for baseline differences between the 2 cohorts.

resultsA total of 666 consecutive patients underwent SAVR with the 2 devices. ME was implanted in 367 patients (55.1%) and Intuity in 299 (44.9%). ME size 19 or 21 was used in 105 patients (35.1%), and Intuity size 19 or 21 in 115 patients (31.3%). Our study population comprised 220 patients. There were no significant differences in postoperative complications. Intuity demonstrated significantly lower gradients overall (mean gradients: 12 mmHg vs 16 mmHg, P < 0.001) and for size 21 (mean gradients: 12 mmHg vs 15 mmHg, P < 0.001). Mid-term survival and rehospitalization rates were similar between the 2 devices (5-year rehospitalization rate: 17% ME vs 20.9% Intuity, P = 0.57; 5-year survival: 81.9% ME vs 88% Intuity, P = 0.761).

conclusionsIn patients with small aortic annuli, RD bioprostheses provide superior haemodynamic outcomes compared to conventional stented valves. However, perioperative outcomes, mid-term survival, and rehospitalization rates are similar between the 2 devices.

Indexed as

Aortic ValveAortic Valve StenosisBioprosthesisHeart Valve ProsthesisHeart Valve Prosthesis ImplantationStentsAgedAged, 80 and overFemaleHemodynamicsHumansMaleMiddle AgedPostoperative ComplicationsPropensity ScoreProsthesis Designrapid-deployment valvesmall anulusstented aortic valvesurgical aortic valve replacement

Identifiers

PMID41071054
PMCPMC12596474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.