Evidence map›Paper›PMID 41070719›Full record

ArticleeLife2025

Forecasting the spatial spread of an Ebola epidemic in real time: Comparing predictions of mathematical models and experts.

James D Munday, Alicia Rosello, W John Edmunds, Sebastian Funk

Abstract readComparative Study
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Local Influenza Forecasts Outperform State-Level Forecasts in the United States.medRxiv : the preprint server for health sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James D Munday *Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID https://orcid.org/0000-0002-6206-7134
Alicia Rosello *Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID https://orcid.org/0000-0002-0737-5679
W John Edmunds *Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Sebastian Funk *Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID https://orcid.org/0000-0002-2842-3406

Funding

National Institute for Health and Care Research VEEPED: PR-OD-1017-20002Wellcome TrustWellcome Trust 10.35802/210758
6 · The paper itself

Abstract

Background: Ebola virus disease outbreaks can often be controlled, but require rapid response efforts frequently with profound operational complexities. Mathematical models can be used to support response planning, but it is unclear if models improve the prior understanding of experts. Methods: We performed repeated surveys of Ebola response experts during an outbreak. From each expert, we elicited the probability of cases exceeding four thresholds between 2 and 20 cases in a set of small geographical areas in the following calendar month. We compared the predictive performance of these forecasts to those of two mathematical models with different spatial interaction components. Results: An ensemble combining the forecasts of all experts performed similarly to the two models. Experts showed stronger bias than models forecasting two-case threshold exceedance. Experts and models both performed better when predicting exceedance of higher thresholds. The models also tended to be better at risk-ranking areas than experts. Conclusions: Our results support the use of models in outbreak contexts, offering a convenient and scalable route to a quantified situational awareness, which can provide confidence in or to call into question existing advice of experts. There could be value in combining expert opinion and modelled forecasts to support the response to future outbreaks. Funding: This study was partly funded by the Department of Health and Social Care using UK Aid funding 47 and is managed by the National Institute for Health and Care Research (VEEPED: PR-OD-1017- 48 20002; AR and WJE). This study was partly funded by the Wellcome Trust (210758/Z/18/Z : JDM 49 and SF). The views expressed in this publication are those of the authors and not necessarily 50 those of the funders.

Indexed as

EpidemicsHemorrhagic Fever, EbolaModels, TheoreticalDisease OutbreaksForecastingHumansEbolaepidemiologyexpert ellicitationforecastsglobal healthmathematical modellingspatial modellingviruses

Identifiers

PMID41070719
PMCPMC12513718

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.