Evidence map›Paper›PMID 41070615›Full record

ReviewInternational journal of oncology2025

Exosomal microRNAs: A new role in the diagnosis and treatment of lung cancer metastases (Review).

Xin Li, Jian Wang, Weipeng Ge, Xinbo Chen

Abstract readReview
In one paragraph

Review in International journal of oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xin LiDepartment of Pain, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.
Jian WangDepartment of Oncology, Lijin County Central Hospital, Dongying, Shandong 257400, P.R. China.
Weipeng GeDepartment of Pain, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.
Xinbo ChenDepartment of Gastroenterology, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer (LC) is a lethal malignancy that can pose a serious risk to a patient's health. Tumor metastasis is associated with a shorter survival and poor therapeutic outcomes. Epithelial‑mesenchymal transition, cell proliferation and angiogenesis are the key drivers of metastasis, which accounts for cancer malignancy. Exosomal microRNAs (miRNAs) are miRNAs packed and released in exosomes. Exosomal miRNAs promote the metastasis of LC. As the amount and type of exosomal miRNAs are disrupted in pathological situations, they may serve as markers for the diagnosis and treatment of LC. The present review summarizes the effects and underlying mechanisms of exosomal miRNAs in LC metastasis. It also provides an overview of the potential of exosomal miRNAs as diagnostic indicators and therapeutic targets for LC metastasis, highlighting novel avenues for future tailored therapies.

Indexed as

Biomarkers, TumorExosomesLung NeoplasmsMicroRNAsEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansNeoplasm MetastasisBiomarkers, TumorMicroRNAsexosomallung cancermetastasismicroRNAs

Identifiers

PMID41070615
PMCPMC12532287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.