Evidence map›Paper›PMID 41070574›Full record

ArticleJournal of oral & facial pain and headache2025

A retrospective evaluation of the clinical efficacy of occlusal splint therapy combined with manual therapy in patients with anterior disc displacement without reduction.

Jingke Gu, Yukang Zhang, Wanghui Ding, Shuyan Liu

Abstract read
In one paragraph

Article in Journal of oral & facial pain and headache, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jingke Gu *Center for Plastic & Reconstructive Surgery, Department of Dental Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), 310014 Hangzhou, Zhejiang, China.
Yukang Zhang *Xianju Traditional Chinese Medicine Hospital, 317300 Taizhou, Zhejiang, China.
Wanghui DingStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, 310000 Hangzhou, Zhejiang, China.
Shuyan LiuCenter for Plastic & Reconstructive Surgery, Department of Dental Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), 310014 Hangzhou, Zhejiang, China.

Funding

Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project 2023ZL276
6 · The paper itself

Abstract

backgroundThe study aimed to retrospectively evaluate the clinical efficacy of a computer-aided design/computer-aided manufacturing (CAD/CAM)-fabricated occlusal splint combined with manual therapy in patients diagnosed with anterior disc displacement without reduction (ADDwoR) of the temporomandibular joint (TMJ).

methodsThe medical records of 65 adult patients with ADDwoR, treated between March 2022 and March 2023, were reviewed and allocated into three treatment groups based on the interventions they received, namely, occlusal splint therapy alone (n = 22), occlusal splint therapy combined with manual therapy (n = 22), or health education alone (n = 21). All participants received standardized health education. Clinical outcomes, including Maximum Mouth Opening (MMO), Visual Analog Scale (VAS) for pain, and the Mandibular Functional Impairment Questionnaire (MFIQ), were assessed at baseline and one and three months post-treatment by blinded evaluators. Statistical analyses were conducted using Python with Welch's analysis of variance (ANOVA) and repeated measures ANOVA, and significance was set at

resultsThe baseline demographic and clinical characteristics were similar among the three groups (all

conclusionsThis short-term non-randomized retrospective study suggests that combining CAD/CAM-fabricated occlusal splint therapy with manual therapy yielded superior pain relief and functional improvement compared to splint therapy alone or health education in patients with ADDwoR.

Indexed as

Joint DislocationsMusculoskeletal ManipulationsOcclusal SplintsTemporomandibular Joint DisordersAdultCombined Modality TherapyComputer-Aided DesignFemaleHumansMaleMiddle AgedPain MeasurementRetrospective StudiesTemporomandibular Joint DiscTreatment OutcomeYoung AdultAnterior disc displacement without reduction (ADDwoR)Mandibular functional impairment questionnaire (MFIQ)Manual therapyMaximum mouth opening (MMO)Occlusal splint (CAD/CAM)Temporomandibular disor-ders (TMD)Visual analog scale (VAS)

Identifiers

PMID41070574
PMCPMC12520436

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.