Evidence map›Paper›PMID 41070564›Full record

SynthesisJournal of oral & facial pain and headache2025

Impact of zygomaticomaxillary complex fracture on masticatory muscle dysfunction and pain: systematic review and observational meta-analysis.

Sunil Kumar Vaddamanu, Imran Khalid, Rayan Ibrahim H Binduhayyim, Ali Y Alsaeed, Shaya S Alshahrani, Abosofyan Salih Atta Elfadeel Mohamed Salih, Maria Maddalena Marrapodi, Giuseppe Minervini

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of oral & facial pain and headache, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sunil Kumar VaddamanuDepartment of Allied Dental Health Sciences, College of Applied Medical Sciences, King Khalid University, 62561 Abha, Saudi Arabia.
Imran KhalidDepartment of Oral and Maxillofacial Surgery, College of Dentistry, King Khalid University, 62561 Abha, Saudi Arabia.
Rayan Ibrahim H BinduhayyimDepartment of Allied Dental Health Sciences, College of Applied Medical Sciences, King Khalid University, 62561 Abha, Saudi Arabia.
Ali Y AlsaeedDepartment of Restorative Dental Sciences, College of Dentistry, King Khalid University, 62561 Abha, Saudi Arabia.
Shaya S AlshahraniCollege of Dentistry, King Khalid University, 62561 Abha, Saudi Arabia.
Abosofyan Salih Atta Elfadeel Mohamed SalihDepartment of Oral and Maxillofacial Surgery, College of Dentistry, King Khalid University, 62561 Abha, Saudi Arabia.
Maria Maddalena MarrapodiDepartment of Woman, Child and General and Specality Surgery, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.
Giuseppe MinerviniMultidisciplinary Department of Medical Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.

Funding

King Khalid University RA.KKU/19/45
6 · The paper itself

Abstract

backgroundZygomaticomaxillary complex (ZMC) fractures significantly affect facial aesthetics and masticatory function, necessitating effective rehabilitation strategies. This systematic review and meta-analysis investigated the effects of fractures on masticatory muscle function and pain management.

methodsAdhering to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, conducted a comprehensive search across databases, including PubMed, MEDLINE, Embase, PsycINFO, Web of Knowledge, Scopus, CINAHL, LILACS, SciELO, Cochrane and Google Scholar, and selected studies that assessed masticatory function through metrics such as bite force, electromyography activity, and post-intervention pain levels in patients with ZMC fractures. Data were synthesized using a random-effects model.

resultsFourteen studies were included, which highlighted diminished bite force and altered muscle activity patterns in patients with ZMC fractures. Significant improvements in muscle function and pain management were observed postoperatively, with interventions including surgical repair and physical therapy proving to be effective. The meta-analysis demonstrated a marked reduction in pain, substantiated by changes in visual analog scale scores from an average of 7.5 pre-operatively to 2.3 post-operatively.

conclusionsZMC fractures profoundly affect masticatory efficiency and cause notable pain, which can be substantially alleviated by targeted surgical and therapeutic interventions. THE PROSPERO REGISTRATION: This systematic review and meta-analysis followed the PRISMA guidelines and was registered in PROSPERO (CRD42024595963).

Indexed as

Facial PainMasticatory MusclesMaxillary FracturesZygomatic FracturesBite ForceHumansObservational Studies as TopicPain ManagementPain MeasurementBite forceElectromyographyFacial traumaMasticatory muscle functionPain managementZygomaticomaxillary complex fractures

Identifiers

PMID41070564
PMCPMC12520437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.