ArticleJournal of oral & facial pain and headache2025
Integration of nociceptive activity from orofacial, cranial and cervical regions in the trigeminocervical nucleus: a scoping review with clinical implications.
Article in Journal of oral & facial pain and headache, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transcranial direct current stimulation combined with rehabilitation training for chronic spinal pain: a systematic review and Meta-analysis.Frontiers in neurology · 2026Pooled it
- Neuroimmune alterations and nociceptive behavior in oral carcinogenesis in rats.European journal of oral sciences · 2026Article
- Static sagittal cervical alignment, pain, and jaw functional limitation across temporomandibular disorder subtypes: a cross-sectional study.BMC oral health · 2026Article
- Localization of pain in patients with probable bruxism: a cross-sectional pain-drawing and heat-map analysis.BMC oral health · 2026Article
- Factors Associated With Craniocervical and Otological Symptoms in Healthcare Workers During Covid-19 Pandemic: A Cross-Sectional Study.Journal of oral rehabilitation · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A connection between orofacial, cranial and cervical regions has been documented through the trigeminocervical nucleus (TCN), but the predominant direction (orofacial/cranial-to-cervical or cervical-to-orofacial/cranio) of this connection still remains unclear. This scoping review was designed to determine the dominant direction of the connection between these two areas. Searches were conducted by combining these concepts: TCN, cervical and face/jaw/head region. Eighty-three studies were included. The most predominant direction was reported to be from the orofacial/cranial to the cervical region, with most of the studies conducted in mammals. The clinical implications of these findings for the spread and referral of pain between these regions are examined and discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.