Evidence map›Paper›PMID 41070534›Full record

SynthesisJournal of oral & facial pain and headache2025

Prevalence of temporomandibular disorder in irritable bowel syndrome (IBS) patients: a systematic review.

Michele Cricri, Gaetano Luglio, Francesca Tropeano, Antonio Miele, Giovanni Domenico De Palma, Maria Maddalena Marrapodi, Diana Russo, Marco Cicciù, Giuseppe Minervini

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of oral & facial pain and headache, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michele CricriEndoscopic Surgery Unit, Department of Clinical Medicine and Surgery, University of Naples "Federico II", 80131 Naples, Italy.
Gaetano LuglioEndoscopic Surgery Unit, Department of Public Health, University of Naples "Federico II", 80131 Naples, Italy.
Francesca TropeanoEndoscopic Surgery Unit, Department of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Naples, Italy.
Antonio MieleEndoscopic Surgery Unit, Department of Clinical Medicine and Surgery, University of Naples "Federico II", 80131 Naples, Italy.
Giovanni Domenico De PalmaEndoscopic Surgery Unit, Department of Clinical Medicine and Surgery, University of Naples "Federico II", 80131 Naples, Italy.
Maria Maddalena MarrapodiDepartment of Woman, Child and General and Specialist Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Diana RussoMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Marco CicciùDepartment of Biomedical and Surgical and Biomedical Sciences, Catania University, 95123 Catania, Italy.
Giuseppe MinerviniMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTemporomandibular disorders (TMD) refer to a collection of pathological conditions that impact the stomatognathic system, often associated with psychiatric comorbidities. Interestingly, previous studies have reported a higher prevalence of TMD in individuals affected by irritable bowel syndrome (IBS), a condition commonly linked to stress-induced psychosomatic factors. The aim of this systematic review is to clarify the prevalence of TMD in IBS-diagnosed patients.

methodsA systematic search was conducted in PubMed, Scopus, Web of Science and Cochrane Library databases up to May 2024, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. Eligibility criteria included studies reporting prevalence data on TMD in IBS patients. Study quality was assessed using the Risk of Bias in Non-randomized Studies-of Exposure (ROBINS-E) tool.

resultsA total of five studies, involving 3138 patients, were included. TMD prevalence was significantly higher in IBS patients compared to pooled controls. However, no significant differences were observed among IBS subtypes regarding TMD prevalence.

conclusionsThis review highlights a substantially higher prevalence of TMD in IBS patients compared to the general population, suggesting a shared pathophysiological mechanism likely linked to stress response systems. These findings underscore the need for a multidisciplinary approach to patient management and emphasize the importance of further research to explore the causal links and underlying mechanisms between IBS and TMD. THE PROSPERO REGISTRATION: The protocol has been registered on the International Prospective Register of Systematic Reviews (PROSPERO) with the number CRD42024542233.

Indexed as

Irritable Bowel SyndromeTemporomandibular Joint DisordersHumansPrevalenceIrritable bowel syndromeMeta-analysisPrevalencePsychosomatic disordersSystematic reviewTemporomandibular disorders

Identifiers

PMID41070534
PMCPMC12520419

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.