Evidence map›Paper›PMID 41070373›Full record

ArticleThe ... Midwest Symposium on Circuits and Systems conference proceedings : MWSCAS. Midwest Symposium on Circuits and Systems2024

On-Chip Active Pulse-Clamp Stimulation (APCS) for Rapid Recovery, Charge-Balanced Neural Stimulation.

Fnu Tala, Benjamin C Johnson

Abstract read
In one paragraph

Article in The ... Midwest Symposium on Circuits and Systems conference proceedings : MWSCAS. Midwest Symposium on Circuits and Systems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. On-Chip Active Pulse-Clamp Stimulation (APCS) for Rapid Recovery, Charge-Balanced Neural Stimulation.The ... Midwest Symposium on Circuits and Systems conference proceedings : MWSCAS. Midwest Symposium on Circuits and Systems · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fnu TalaElectrical and Computer Engineering, Boise State University, Boise, ID USA.
Benjamin C JohnsonElectrical and Computer Engineering, Boise State University, Boise, ID USA.

Funding

Women's health: interplay of maternal diet and key demographics on neurological health in the rural frontier and remote WestP20GM103408 · NIGMS · UNIVERSITY OF IDAHO · PI Carolyn Hovde Bohach · 2012 to 2026
$59.8M
VPS35 D620N inhibits autophagy through disrupted hyaluronic acid-CD44 signalingP20GM109095 · NIGMS · BOISE STATE UNIVERSITY · PI OXFORD, JULIA THOM · 2014 to 2023
$22.7M
Optimizing Deep Brain Stimulation for Parkinson's Disease.P20GM148321 · NIGMS · BOISE STATE UNIVERSITY · PI Paul Henry Davis · 2023 to 2026
$10.2M
PAR04-122, Extramural Research Facilities Construction:*C06RR020533 · NCRR · BOISE STATE UNIVERSITY · PI RUDIN, MARK JOSEPH · 2010 to 2010
$4.0M
NCRR NIH HHS C06 RR020533NIGMS NIH HHS P20 GM103408NIGMS NIH HHS P20 GM109095NIGMS NIH HHS P20 GM148321
6 · The paper itself

Abstract

Rapid and charge-balanced electrical stimulation is imperative for neurostimulation implants aimed at chronic safety and closed-loop usage. We present an innovative stimulation technique, Active Pulse-Clamp Stimulation (APCS), designed to ensure dependable charge balance with rapid recovery. The APCS technique has two distinctive modes, linear and slewing modes, both incorporated into the on-chip APCS system. APCS employs discrete-time feedback to sense the residual voltage across the electrode's double-layer capacitance, expediting the settling of the electrode interface by either grounding (slewing) or clamping with an amplifier (linear). APCS combines the strengths of both biphasic stimulation and passive recharge, with a customizable recovery time constant set by the user while offering a guaranteed charge balance for safety. To showcase the proof-of-concept for APCS, we implemented the on-chip APCS using a 180nm CMOS process. We demonstrated combined APCS functionality using a benchtop electrode model and a real clinical deep brain stimulation (DBS) electrode in vitro.

Indexed as

Active Pulse-Clamp Stimulation (APCS)charge balancingCMOSelectrodesneurostimulation

Identifiers

PMID41070373
PMCPMC12507097

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.