ArticleAlzheimer's & dementia (New York, N. Y.)
Neurovascular de-coupling underlies dual-task cost across cognitive abilities.
Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Neurovascular de-coupling underlies dual-task cost across cognitive abilities.Alzheimer's & dementia (New York, N. Y.)Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionWe tested the hypothesis that increased middle cerebral artery velocity (MCA velocity) during complex motor (overground walking) and cognitive tasks (e.g., dual task) is associated with cognitive performance in older adults with varying levels of cognitive ability.
methodsFifty-six participants (19 females, 75 ± 7 years old) completed a seated single task that assessed working memory performance; a walking single task, assessing overground walking gait speed; and a dual task, combining both. Continuous MCA velocity was collected, and participants completed a Montreal Cognitive Assessment (MoCA).
resultsHigher MCA velocity was associated with faster gait speed, better working memory performance, and greater MoCA scores (all DISCUSSION: The functional response of cerebral blood flow with these tests suggests vascular properties may be considered a biomarker indicative of subclinical cognitive function during walking tasks. Highlights: Mobile devices simultaneously assessed neurovascular coupling and dual-task cost.Middle cerebral artery velocity (MCA velocity) is negatively associated with dual-task cost.MCA velocity is associated with gait speed, working memory, and Montreal Cognitive Assessment scores.MCA velocity decreased from controls to mild cognitive impairment to dementia.Novel methodological approach to utilize MCA velocity during overground walking, single-tasks, and dual-tasks.
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