ArticleJGH open : an open access journal of gastroenterology and hepatology2025
Association Between Digestive Diseases, Nighttime Sleep, and Depressive Symptoms Among the Middle-Aged and Elderly Adults: A Mediation Analysis.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Association Between Digestive Diseases, Nighttime Sleep, and Depressive Symptoms Among the Middle-Aged and Elderly Adults: A Mediation Analysis.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To explore the mediating effect of nighttime sleep duration between digestive diseases and depressive symptoms among middle-aged and elderly adults, so as to guide clinical intervention and treatment of depression related to digestive diseases. Methods: Based on the data of the China Health and Retirement Longitudinal Study (CHARLS) from 2015 to 2020, difference analysis, Spearman correlation analysis, and multivariate logistic regression were conducted to analyze the relationships among digestive diseases, nighttime sleep duration, and depressive symptoms. The mediating effect model was established and tested by the Bootstrap method. Results: The prevalence rate of digestive diseases was 23.05%, and the detection rate of depressive symptoms was 35.90%. Correlation and regression analysis indicated that digestive diseases (OR = 1.62, 95% CI: 1.45-1.81) and insufficient nighttime sleep (OR = 2.22, 95% CI: 2.01-2.45) significantly impacted depressive symptoms. The results of the mediating effect model showed that insufficient nighttime sleep had a partial mediating effect between digestive diseases and depressive symptoms among middle-aged and elderly adults. Conclusion: Digestive diseases can lead to insufficient nighttime sleep and promote the occurrence of depressive symptoms among middle-aged and elderly adults. Therefore, in clinical practice, when treating digestive patients with comorbid depression, the quality and duration of their nighttime sleep should not be ignored. Improving sleep conditions is expected to alleviate depressive symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.