Evidence map›Paper›PMID 41070160›Full record

ArticleFrontiers in pediatrics2025

Quantitative ¹³C-urea breath test values predict peptic ulcer risk in

Xiaoting Pan, Youtao Chen, Haibo Li, Hong Ye

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Association of TyG and TyG/HDL withFrontiers in medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoting Pan *Fujian Children's Hospital, Fujian Branch of Shanghai Children's Medical Center, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Youtao Chen *Fujian Children's Hospital, Fujian Branch of Shanghai Children's Medical Center, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Haibo LiFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Hong YeFujian Children's Hospital, Fujian Branch of Shanghai Children's Medical Center, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The quantitative ¹³C-urea breath test (¹³C-UBT) is valuable for diagnosing Methods: In this retrospective study, 1,034 consecutive children aged 3-18 years undergoing ¹³C-UBT with endoscopy and histopathological evaluation at Fujian Children's Hospital (May 2021-May 2025) were enrolled. DOB cutoff values were determined by ROC analysis. Logistic regression and restricted cubic spline (RCS) analyses evaluated associations between DOBs and ulcer risk. Results: The optimal pediatric-specific cutoff was 5.285% [Sensitivity 84%, Specificity 90%, area under the curve (AUC) 0.879]. Children with ulcers had significantly higher median DOBs than those without (3.1% vs. 1.9%; Conclusions: A DOB cutoff of 5.285‰ provides excellent diagnostic accuracy for pediatric

Indexed as

13C-urea breath testbacterial loaddiagnostic accuracyHelicobacter pyloripediatric gastroenterologypeptic ulcer

Identifiers

PMID41070160
PMCPMC12504025

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.