Evidence map›Paper›PMID 41070089›Full record

ArticleFrontiers in cardiovascular medicine2025

Comparative analysis of cardiac function before LVAD implantation in patients with and without early, acute right heart failure: insights from cardiac magnetic resonance.

Carl-Thaddäus Braun, Hermann Körperich, Michiel Morshuis, Sabina P W Guenther, Lech Paluszkiewicz, Nikolai Hulde, Henrik Fox, Sebastian V Rojas, Jan Gummert, René Schramm

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carl-Thaddäus BraunClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Hermann KörperichInstitute for Radiology, Nuclear Medicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Michiel MorshuisClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Sabina P W GuentherClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Lech PaluszkiewiczClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Nikolai HuldeInstitute for Anesthesiology and Pain Therapy, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Henrik FoxClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Sebastian V RojasClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Jan GummertClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
René SchrammClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early acute right heart failure (eaRHF) during left ventricular assist device (LVAD) implantation significantly impacts patient survival and complicates perioperative management. Although numerous clinical, echocardiographic, and hemodynamic risk factors have been identified, accurately predicting eaRHF remains challenging. Cardiac magnetic resonance (CMR) provides a precise, non-invasive evaluation of cardiac structure and function and may enhance risk stratification eaRHF. This study aims to assess the predictive value of preoperative CMR-derived parameters, comparing their utility to established echocardiographic and right heart catheterization (RHC) markers for identifying eaRHF. Methods: This retrospective analysis was conducted on 55 patients who received CMR before LVAD implantation at our center between 2018 and 2024. Of these 55 patients, 40 had image quality sufficient for offline analysis. Patients receiving a temporary right ventricular assist device (tRVAD) intraoperatively were defined as having eaRHF. Receiver Operating Characteristic (ROC) analysis was used to evaluate the predictive capability of CMR, echocardiographic, and RHC parameters. Results: Ten patients (25%) developed eaRHF. Preoperative bilirubin levels were significantly higher in the eaRHF group (1.6 mg/dl vs. 1.1 mg/dl, Conclusion: Hemodynamic parameters from RHC demonstrated the strongest predictive capability for eaRHF. However, selected CMR-derived parameters, especially indexed RV-EDV and RV GRS, offer moderate predictive value and may serve as adjunctive tools in preoperative risk stratification for LVAD candidates.

Indexed as

cardiovascular imagingCMRheart failureLVADright heart failure

Identifiers

PMID41070089
PMCPMC12504228

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.