Evidence map›Paper›PMID 41070048›Full record

SynthesisFrontiers in oral health2025

Gag reflex management in dental practice: a bibliometric analysis from 2000 to 2025.

Yena Gan, Jinwei Huang, Duoduo Li, He Xu, Sheng Han, He Zhu, Zening Wei, Zhigang Cai

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yena Gan *Department of Academic Research, International Research Center for Medicinal Administration, Peking University, Beijing, China.
Jinwei Huang *Department of General Dentistry Ⅱ, Peking University School and Hospital of Stomatology, Beijing, China.
Duoduo LiDepartment of Tuina and Pain, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
He XuNational Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
Sheng HanDepartment of Academic Research, International Research Center for Medicinal Administration, Peking University, Beijing, China.
He ZhuDepartment of Academic Research, International Research Center for Medicinal Administration, Peking University, Beijing, China.
Zening WeiInstitute of Medical Innovation and Research & Medical Research Center, Peking University Third Hospital, Beijing, China.
Zhigang CaiNational Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The gag reflex is a common challenge in dental practice, often causing discomfort and leading to treatment avoidance, especially during procedures like taking dental impressions. Although both pharmacological and non-pharmacological treatments are utilized to manage the gag reflex, current evidence supporting the routine use of these interventions is limited, highlighting the need for further research. To optimize gag reflex management and identify future research trends through a bibliometric analysis. Methods: Data from eligible studies were extracted through a comprehensive search and various analyses, including descriptive bibliometric, citation, keyword, and thematic analyses. Group comparisons were made between Asian and non-Asian groups to assess the differences and trends between the two regions. Results: Between 2000 and 2025, 47 studies were published, with an average annual increase of 4.68%. Japan, Iran, India, the USA, and Turkey each contributed at least 10 studies, and studies from Lebanon had the highest citation frequency. The majority of studies were randomized controlled trials (46.81%), followed by case reports (46.81%) and case series (6.38%). Most studies (80.85%) focused on adults undergoing extractions (38.30%), restorations (31.91%), and dental impressions (14.89%). Interventions primarily targeted nausea and vomiting (74.47%) using pharmacological treatments such as lidocaine, propofol, and midazolam and non-pharmacological methods such as acupuncture, acupressure, and Transcutaneous Electrical Nerve Stimulation. Significant differences were observed between Asian and non-Asian groups in publication years, study designs, demographics, treatments, and clinical outcomes. Conclusions: Gag reflex management has advanced with pharmacological treatments for immediate relief and increased use of non-pharmacological methods such as acupuncture and laser stimulation, particularly in Japan, Turkey, and the USA. However, challenges such as small-scale studies, limited follow-ups, and underrepresentation of children and adolescents highlight the need for larger studies, standardized tools, and inclusive approaches for diverse patient groups. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420250650382, identifier (CRD420250650382).

Indexed as

acupuncturebibliometric analysisdental treatmentgag reflextreatment avoidance

Identifiers

PMID41070048
PMCPMC12504200

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.