Evidence map›Paper›PMID 41070028›Full record

ArticleFrontiers in nutrition2025

Chemical profiling, antioxidant, and antibacterial properties of

Eliana-Yissel Aguilera-Angel, Diego Ballesteros-Vivas, Ricardo Vera-Bravo, Néstor García, Jorge-Eliecer Robles-Camargo, Geison Modesti Costa, Mauricio Espinal-Ruiz, Juan Pablo Caicedo-Trejos, Ana Karina Carrascal Camacho, Izlia-Jazheel Arroyo-Maya and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Glucosinolate Derivatives: Emerging Anti-Inflammatory Agents.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Eliana-Yissel Aguilera-AngelDepartamento de Nutrición y Bioquímica, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.
Diego Ballesteros-VivasDepartamento de Nutrición y Bioquímica, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.
Ricardo Vera-BravoDepartamento de Química, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.
Néstor GarcíaDepartamento de Biología, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.
Jorge-Eliecer Robles-CamargoDepartamento de Química, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.
Geison Modesti CostaDepartamento de Química, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.
Mauricio Espinal-RuizCenter for Research in Energy and Environment (CREE), University of Missouri of Science and Technology, Rolla, MO, United States.
Juan Pablo Caicedo-TrejosLaboratorio de Microbiología de Alimentos, Grupo de Biotecnología Ambiental e Industrial, Departamento de Microbiología, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.
Ana Karina Carrascal CamachoLaboratorio de Microbiología de Alimentos, Grupo de Biotecnología Ambiental e Industrial, Departamento de Microbiología, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.
Izlia-Jazheel Arroyo-MayaDepartamento de Procesos y Tecnología - División de Ciencias Naturales e Ingeniería, Universidad Autónoma Metropolitana - Unidad Cuajimalpa, Ciudad de México, Mexico.
Elena IbáñezFoodomics Laboratory, Institute of Food Science Research (CIAL) (CSIC-UAM), Madrid, Spain.
Alejandro CifuentesFoodomics Laboratory, Institute of Food Science Research (CIAL) (CSIC-UAM), Madrid, Spain.
Valentina Guzmán-PérezDepartamento de Nutrición y Bioquímica, Facultad de Ciencias - Pontificia Universidad Javeriana, Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nasturtium ( Methods: The aim of this study was to identify the bioactive compounds and functional potential of nasturtium leaves and flowers collected in Cogua, Cundinamarca (Colombia). For this purpose, fresh samples were harvested, processed, and subjected to a preliminary phytochemical analysis. Methanolic and ethanolic extracts were prepared, and total glucosinolates, phenolics, and flavonoids were quantified. Chemical profiling was performed using UHPLC-q-TOF-MS/MS, while functional properties were assessed through antioxidant and antibacterial assays. Results: The ethanolic extract (70% v/v ethanol/water) from leaves retained phenolic compounds (2.10 ± 0.19 g GAE/g DS) and flavonoids (0.15 ± 0.02 g QE/g DS) which are linked to antioxidant activity, and benzyl glucosinolate (8.47 ± 1.68 μmol SE/g DW), whose hydrolysis product, benzyl isothiocyanate, is associated with antibacterial effects. Consistent with this, Enterococcus faecalis (Gram-positive) showed the lowest minimum inhibitory concentration (MIC, 15.6 mg/mL), while Conclusion: This study provides the first report of glucosinolate content in nasturtium cultivated in Colombia and describes the preparation and characterization of an extract obtained with generally recognized as safe (GRAS) solvents. The findings highlight its potential application in functional foods and nutraceuticals.

Indexed as

antibacterial activityantioxidant capacitybenzyl glucosinolatenasturtiumTropaeolum majus

Identifiers

PMID41070028
PMCPMC12507335

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.