Evidence map›Paper›PMID 41070007›Full record

ArticleExpert review of ophthalmology2025

Infectious etiologies of conjunctival tumors.

Osmel P Alvarez, David Monroy, Soraiya Thura, Michael Antonietti, Sohaib Fasih-Ahmad, Paula A Sepulveda-Beltran, Sara Culbertson, Sander R Dubovy, Anat Galor, Carol L Karp

Abstract read
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In one paragraph

Article in Expert review of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Osmel P AlvarezDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-8836-5826
David MonroyDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Soraiya ThuraDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Michael AntoniettiDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Sohaib Fasih-AhmadDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Paula A Sepulveda-BeltranDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Sara CulbertsonDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Sander R DubovyDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Anat GalorDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-3026-6155
Carol L KarpDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Victor L Perez · 2004 to 2026
$12.2M
Differentiation of Clinical Phenotypes of Inflammatory and Neuropathic Ocular Pain Conditions with Morphologic Measures and Functional Brain ImagingU01EY034686 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Eric Alan Moulton · 2022 to 2026
$4.7M
Tear protein biomarkers of refractive surgery painR61EY032468 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI AICHER, SUE A, GALOR, ANAT · 2020 to 2022
$2.0M
BLRD VA I01 BX004893CSRD VA I01 CX002015NEI NIH HHS P30 EY014801NEI NIH HHS R61 EY032468NEI NIH HHS U01 EY034686
6 · The paper itself

Abstract

Introduction: Infectious agents have been associated with a variety of conjunctival tumors, including lymphoma, ocular surface squamous neoplasia (OSSN), papilloma, and Kaposi sarcoma. Areas covered: We discuss the infectious etiologies of certain conjunctival tumors including conjunctival lymphoma ( Expert opinion: It is important for the clinician to recognize when tumors of the conjunctiva may be infection-associated. A detailed history and exam are the most important first step in diagnosis; this may be supplemented by tools such as high-resolution optical coherence tomography. For some tumors, the specific causative agent may influence treatment options and outcomes. For others, data suggest the infectious agent does not influence treatment or outcomes, but it is important nonetheless to be aware as further research on these tumors continues. Additionally, there is exciting research investigating novel and minimally invasive diagnostic and treatment options for conjunctival tumors, including treatments that target the infectious agent directly.

Indexed as

conjunctival Kaposi sarcomaconjunctival lymphomaconjunctival papillomaConjunctival tumorsinfection-related tumorsocular surface squamous neoplasia

Identifiers

PMID41070007
PMCPMC12506805

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.