ArticleFrontiers in psychiatry2025
Global, regional, and national burden of mental disorders and substance use disorders in older adults from 1990 to 2021: a systematic analysis and future trend prediction study.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Multidimensional determinants of depression and non-depression in older adults: evidence from national data.BMC geriatrics · 2026Article
- Social engagement and depressive symptoms in Korean older adults: The potential moderating role of employment status.PloS one · 2026Article
- Association Between Self-Reported Psychiatric Diseases and Oral Health Among Older Adults.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric DentistryArticle
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Authors and funding
5 authors.
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Abstract
Introduction: As the global population ages, mental health has become a major public health issue affecting healthy aging. To estimate the burden, trends, and inequalities of mental disorders and substance use disorders (SUDs) among older adults aged ≥60 years at the global, regional, and national levels from 1990 to 2021. Methods: Data from the Global Burden of Disease Study 2021. The study focused on the burden of mental health conditions, analyzing mental disorders and SUDs prevalence, years lived with disability (YLDs), and average annual percentage change (AAPC), encompassing eight age groups (60-64 years, 65-69 years, 70-74 years, 75-79 years, 80-84 years, 85-89 years, 90-94 years, ≥95 years) for both men and women. Results: Globally in 2021, 1.09 billion individuals aged ≥60 years included 161.3 million (14.8%) with mental disorders and 19.2 million (1.8%) with SUDs. Mental disorders accounted for 22.8 million YLDs versus 2.10 million from SUDs in this population. From 1990 to 2021, age standardized prevalence of mental disorders increased by 3.7%, while SUDs declined by 8.7%, with lower SDI levels correlating with higher YLDs burdens overall. Over the next fifteen years, projections indicating stagnant trends in SUDs alongside slight declines in mental disorders highlight persistent unmet needs. Discussion: Global population aging demands heightened prioritization of mental healthcare for older adults. Today, mental and substance use disorders persist as major contributors to disease burden in this population. Our findings call for equitable mental resource allocation, age-adapted diagnostic tools, and policies targeting late-life psychosocial vulnerabilities.
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