Evidence map›Paper›PMID 41069844›Full record

ArticleNon-coding RNA research2025

Exosome-like nanovesicles from

Zhaoyi Wei, Mengxi Zhu, Shan Li, Junling An, Yiwen Liu, Shuying Feng, Tingting Yang, Shegan Gao, Gaofeng Liang

Abstract read
In one paragraph

Article in Non-coding RNA research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. TopicalPharmaceutics · 2026
    Article
  2. Response of aBiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhaoyi WeiHenan International Joint Laboratory of Small Nucleic Acid and Tumor Precision Theranostics, School of Basic Medicine and Forensic Medicine, Henan University of Science & Technology, Luoyang City, Henan Province, 471023, China.
Mengxi ZhuHenan International Joint Laboratory of Small Nucleic Acid and Tumor Precision Theranostics, School of Basic Medicine and Forensic Medicine, Henan University of Science & Technology, Luoyang City, Henan Province, 471023, China.
Shan LiHenan International Joint Laboratory of Small Nucleic Acid and Tumor Precision Theranostics, School of Basic Medicine and Forensic Medicine, Henan University of Science & Technology, Luoyang City, Henan Province, 471023, China.
Junling AnHenan International Joint Laboratory of Small Nucleic Acid and Tumor Precision Theranostics, School of Basic Medicine and Forensic Medicine, Henan University of Science & Technology, Luoyang City, Henan Province, 471023, China.
Yiwen LiuClinical Medical College Henan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang City, Henan Province, 471023, China.
Shuying FengClinical Medical College, Henan University of Chinese Medicine, No. 156, Jinshui East Road, Zhengzhou City, Henan Province, 450046, China.
Tingting YangHenan International Joint Laboratory of Small Nucleic Acid and Tumor Precision Theranostics, School of Basic Medicine and Forensic Medicine, Henan University of Science & Technology, Luoyang City, Henan Province, 471023, China.
Shegan GaoInstitute of Organoids on Chips and Drug Translational Research, Henan Academy of Sciences, Zhengzhou City, Henan Province, 450009, China.
Gaofeng LiangHenan International Joint Laboratory of Small Nucleic Acid and Tumor Precision Theranostics, School of Basic Medicine and Forensic Medicine, Henan University of Science & Technology, Luoyang City, Henan Province, 471023, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Esophageal cancer is one of the common malignant tumors of digestive system. Despite many advances in the treatment of esophageal cancer, many challenges remain. As an endogenous extracellular vesicle, exosomes are increasingly presenting their immense potential in drug delivery. However, it remains a bottleneck to obtain a large quantity of uniform, stable, and multi-component controllable exosomes with low cost and time. Methods: A novel targeted drug delivery system based on exosome-like nanovesicles has been developed using the natural Marine single-celled salt Results: The engineered DENV delivery system was prepared and characterized. It exhibited a uniform particle diameter (approximately 150 nm) with Conclusions: The potential of

Indexed as

anti-PD-L1Drug deliveryDunaliella salinaEsophageal cancerExosome-like nanovesiclesmiR-375

Identifiers

PMID41069844
PMCPMC12504820

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.